Competitive Edge: Codexis, Inc.’s Enzyme Engineering

by Jim Lane (Biofuels Digest) ... Codexis is a world-leading enzyme engineering company, enabling the promise of synthetic biology across multiple industries – from the sustainable manufacturing of pharmaceuticals, food and industrial products, to the expansion of life science tools and the discovery of novel biologic drug candidates. We partner with many of the world’s most innovative companies, working on ~20 enzyme discovery projects in parallel, eventually scaling and manufacturing those enzymes in a range of expression systems.

Q: What stage of development are you?

Decades of improvement of our CodeEvolver technology platform has led to a constantly accelerating flywheel of enzyme discovery output and proprietary knowledge of the interrelationship between enzyme structures and their real-world performance attributes. We engineer enzymes to perform in ways previously unimaginable – e.g. to be stable in the human GI tract or in aggressive solvents; to selectively convert trace components, etc.

The CodeEvolver technology platform can often engineer thousands-fold improvement over a natural enzyme in the same time others may be able to obtain only a tens-fold improvement.

Approximately 1900+ patents and patent applications worldwide, that cover a unique and ever-widening array of chemistries and applications. READ MORE