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Corn’s Next Step Change

by Lisa Gibson (Ethanol Producer Magazine)  ... Developing a corn hybrid traditionally takes seven to 10 years, simply because of the nature of scalability generation to generation—it takes two generations to plant just one acre, Schnable says. But the enormous database

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Synthetic Biology Techniques Significantly Increase Purity of Specialized Plant Oils

(Kansas State University/Phys.Org)  Some of the more commonly known and grown oilseed crops in the U.S. have long been canola, soybeans and sunflowers, but a breakthrough by Kansas State University biochemists could lead to the cover crops pennycress and camelina also

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The Digest’s 2024 Multi-Slide Guide to the Agile BioFoundry

by Jim Lane (Biofuels Digest) How can a public biofoundry develop and demonstrate capabilities that enable commercially-relevant biomanufacturing of a wide range of bioproducts by both new and established industrial hosts? The ABF has operated as a BETO-supported project since 2016.

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Embedding Ethics into the Engineering Biology Pipeline

by Danielle Hamm (Nuffield Bioethics) Engineering biology is not new, some would say it is synthetic biology rebranded. But whether you agree with this, or not, there is no denying that the current interest in engineering biology is palpable. And that a clear driver

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Deconstructing Synthetic Biology across Scales: a Conceptual Approach for Training Synthetic Biologists

by Ashty S. Karim, Dylan M. Brown, Chloé M. Archuleta, Sharisse Grannan, Ludmilla Aristilde, Yogesh Goyal, Josh N. Leonard, Niall M. Mangan, Arthur Prindle, Gabriel J. Rocklin, Keith J. Tyo, Laurie Zoloth, Michael C. Jewett, Susanna Calkins, Neha P. Kamat, Danielle

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The ABCDE Chain: Acetogens, the Baltic forests, Clean fuels, Dorpat, the Enlightenment

by Jim Lane (Biofuels Digest) ... If you have gleaned from earlier editions of The Digest that acetogens can make the useful chemical acetate from waste carbon and green hydrogen, you’ve remembered it well. If recall is sketchy, may I recommend All

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Circe Bioscience Licenses Technology to Decarbonize Industry with Microbes Developed at Wyss Institute at Harvard University

by Lindsay Brownell (Wyss Institute at  Harvard Office of Technology Development) Novel gas fermentation approach enables engineered microbes to eat greenhouse gases and produce valuable products for multiple uses -- The Wyss Institute for Biologically Inspired Engineering at Harvard University announced that Circe,

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Fermbox Bio Introduces EN3ZYME: A Global Solution Transforming Agricultural Waste into Renewable Biofuels and Sustainable Synbio Products

(Fermbox Bio/PR Newswire)  Fermbox Bio, a synthetic biology research and manufacturing company, announces the launch of EN3ZYME, a cutting-edge enzyme cocktail designed to enhance both the efficiency and cost-effectiveness of transforming pre-treated agri-based residues into fermentable, cellulosic sugars. These sugars pave

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AI is Accelerating Materials Science Discovery and Synthesis Exponentially

by Kent Goeking (LEC Partners/Biofuels Digest) One of the key barriers to the economic and technical success of many advanced energy technologies is the sub-optimum performance of critical inorganic materials used as catalysts, electrodes, dielectrics, and photovoltaics.  Oxide materials in particular,

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Strengthening the EU’s Bioeconomy Strategy with Four Policy Recommendations

(European Commission/CORDIS) From policy briefs to social media campaigns, PROMICON points the way to a sustainable bio-based economy. -- The EU-funded PROMICON project has released its first policy brief supporting the 2018 EU Bioeconomy Strategy’s goal to create a sustainable, circular and

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The Digest’s 2024 Multi-Slide Guide to Synonym

by Jim Lane (Biofuels Digest) Synonym is a financing and development platform for essential biomanufacturing infrastructure. Based on a team of cross‑functional experts, they are partnering with synthetic biology companies and capital providers to enable fermentation at scale. CIO Brentan Alexander took

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Biomass to Liquid Fuels: We Need Commercial Scale Gen 2 Success

by Doug Rivers (Lee Enterprise Consulting/Biofuels Digest)  ... And while advances have been made in the materials handling and pretreatment of these feedstocks, commercial scale attempts produce ethanol have been met with multiple and highly visible failures measured in at least hundreds

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Bio Products: Green Materials for an Emerging Circular and Sustainable Economy (De Gruyter Stem)

by Bhima R. Vijayendran (Redwood Innovation Partners) The book is focused on Bio Products derived from renewable resources processed by conventional catalytic thermochemical processes and or emerging bioprocessing techniques including fermentation and synthetic biology. It highlights some of these developments—from discovery,

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Amyris’ Bankruptcy Filing: Complete Details

by Jim Lane (Biofuels Digest) Here follows the complete Amyris statement with respect to its Chapter 11 bankruptcy filing. Amyris, Inc. (Nasdaq: AMRS) (“Amyris” or the “Company”), a leading synthetic biotechnology company accelerating the world’s transition to sustainable consumption through its Lab-to-Market™

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Synthetic DNA Could Help Scientists Modify Genes and Create New Biofuels

(University of Surrey/Newswise) According to quantum biologists from the University of Surrey, the unlocking of the immense potential of laboratory-designed DNA, commonly referred to as synthetic DNA, is poised to revolutionize various fields with groundbreaking advancements. Diverging from naturally occurring DNA, synthetic

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Evogene Receives Grant to Develop Oilseed Crops with High CO2 Assimilation

by Alex Martin (Seed World)  Evogene’s Ag-Seed Division received the EU Horizon grant of €1.2 million euros to support the creation of oilseed crops with high carbon dioxide assimilation and enhanced drought tolerance, according to a release. Evogene will be part of

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Science & Tech Spotlight: Synthetic Biology

(Government Accountability Office) ... This Science & Tech Spotlight describes some of the benefits of synthetic biology and the challenges ahead. For example, while it could be used to engineer living cells that treat disease from within the body, it

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Meet 10 Women Who Are Leading The Synthetic Biology Revolution

by John Cumbers (Forbes) ... These ten powerful women are shaping our world as company leaders, biosecurity experts, policymakers, and philanthropists focused on charting a new course to a more sustainable, equitable, clean, and safe future. Emily Leproust, CEO & Co-founder,

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The Digest’s 2023 Multi-Slide Guide to USDA Efforts in Support of the Bioeconomy

by Jim Lane (Biofuels Digest) The Inflation Reduction Act provides nearly $40 billion for USDA over the next 10 years to improve life and livelihoods in rural communities. Specific investments include: $19.3 billion for climate-smart agriculture on farms, ranches, and

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NREL Launches Synthetic Biology Project to Advance Biofuels

(National Renewable Energy Laboratory/Ethanol Producer Magazine) The pathway that leads us away from unsustainable fossil fuel consumption is not straight and narrow but filled with many branches of possibilities. One of those branches—carbon-negative production of biofuels and biochemicals—is the focus of

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Funding Opportunity Announced through Collaboration Between NSF and DOE DEADLINE April 18, 2023

(U.S. Department of Energy and National Science Foundation) The U.S. Department of Energy (DOE) Bioenergy Technologies Office (BETO) and the National Science Foundation (NSF) announced a collaborative funding opportunity, “Accelerating Innovations in Biomanufacturing Approaches through Collaboration Between NSF and the

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Synbio Powerlabs Secures € 6.6 Million Funding to Build a Revolutionary Biotechnology Plant for Precision Fermentation

(Nutrecon/NewsWires)  Synbio Powerlabs Oy ("Synbio Powerlabs" or the "Company"), a leading Biotech company catalyzing the DNA-Economy by enabling the development of disruptive biotechnologies with precision fermentation, from lab-scale experiments to large scale pilot runs, is pleased to announce it has secured

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The Digest’s 2022 Multi-Slide Guide to Ginkgo Bioworks’ Impact on the Bioeconomy

by Jim Lane (Biofuels Digest) Ginkgo Bioworks—a synthetic biology company—is the leading horizontal platform for cell programming. The mission is to make biology easier to engineer. Customers across industries leverage Ginkgo’s platform to solve some of the world’s most challenging

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The Digest’s 2022 Multi-Slide Guide to Ginkgo Bioworks

by Jim Lane (Biofuels Digest) Ginkgo Bioworks—a synthetic biology company—is the leading horizontal platform for cell programming. Our mission is to make biology easier to engineer. Customers across industries leverage Ginkgo’s platform to solve some of the world’s most challenging

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Launching High School Bioengineers on their Paths to College and Careers from BioBuilder --- December 15, 2022 --- ONLINE

BioMADE EWD Webinar Series: BioBuilder and STEMconnector --  Authentic scientific experiences spark engagement. This BioMADE project is supporting a biomanufacturing track within the BioBuilderClub program – allowing high school students throughout the country to carry out meaningful research with industry-grade

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K-State Scientists Receive Collaborative Grant to Advance Biofuel Production and gricultural Economy

(Kansas State University) Kansas State University researchers are part of a five-year collaborative grant from the U.S. Department of Energy to improve oilseed crops for use as biofuels and other bioproducts. Timothy Durrett, associate professor of biochemistry and molecular biophysics, and Ruth Welti, university

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NextChem Kicks Off the Engineering Phase of Rome Hydrogen Valley (IPCEI HY2USE) and Awards LanzaTech the Process Design Contract for the Circular Ethanol Unit

(LanzaTech/Globe Newswire) The contract relates to the syngas fermentation section of NextChem Hydrogen Valley to produce circular ethanol as initial co-product together with Circular Hydrogen™ -- Maire Tecnimont S.p.A. announces that NextChem, through its subsidiary MyRechemical, has kicked off the engineering

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BOTTLE Project Outlines New Two-Step Process for Turning Mixed Plastic Waste into Valuable Bioproducts

(U.S. Department of Energy) Combining chemical and biological processes is a promising new strategy for the valorization of mixed plastic waste, according to researchers from the Bio-Optimized Technologies to keep Thermoplastics out of Landfills and the Environment (BOTTLE) Consortium. BOTTLE is a collaboration

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Agile BioFoundry Selects New Collaborations

(U.S. Department of Energy) Today, the U.S. Department of Energy (DOE) Bioenergy Technologies Office (BETO) and the Division of Molecular and Cellular Biosciences and the Division of Chemical, Bioengineering, Environmental and Transport Systems at the National Science Foundation (NSF) announced the

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LanzaTech Produces Ethylene from CO2, Changing the Way We Make Products Today

(LanzaTech/Globe Newswire)  Breakthrough Discovery to Replace the Barrel with Synthetic Biology, Addressing One of the Largest Carbon Emitters in the Chemical Industry -- LanzaTech NZ, Inc. (“LanzaTech”), an innovative Carbon Capture and Transformation (“CCT”) company that transforms waste carbon into materials such

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Husker-Led Team Exploiting Oilseeds’ Potential in Biofuels, Bioproducts

by Tiffany Lee (University of Nebraska) A University of Nebraska–Lincoln researcher is leading a team working to unlock the full potential of two oilseeds that may help meet the escalating demand for renewable fuels, industrial chemicals and other bioproducts. The team

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DOE Announces $178 Million to Advance Bioenergy Technology

(U.S. Department of Energy) 37 Projects Will Develop New Technologies That Engineer Plants and Microbes into Bioenergy and Improve Carbon Storage  --  The U.S. Department of Energy (DOE) today announced $178 million for bioenergy research to advance sustainable technology breakthroughs that

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With a €43M EU Grant and €1.2M from a VC, This Startup Plans to Turn CO2 Emissions into Gold

by Mike Butcher (Tech Crunch)  Now Copenhagen-based biotech company SecondCircle thinks it also has a novel approach. It claims to be able to capture CO2 from industrial emitters at the point of emission using “synthetic biology” to develop biocatalysts (bacteria). These then convert the

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Meeting: Biomanufacturing for Bio-Advantaged Fuels --- August 16, 2022 --- ONLINE

Join the U.S. Department of Energy Bioenergy Technologies Office (BETO) and Lawrence Berkeley National Laboratory (LBNL) for a meeting on “Biomanufacturing for Bio-Advantaged Fuels,” August 16, 2022, 12–1:30 p.m. ET. Biofuel molecules commercialized to date primarily rely on high-flux metabolic pathways

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The Digest’s 2022 Multi-Slide Guide to Twist Bioscience

by Jim Lane (Biofuels Digest) Welcome to the absolute starting point of the bioeconomy – strain development means manufacturing synthetic DNA and investing in DNA products — that’s the world of Twist. It’s powering everything from pharma to fuels. Here

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Phytonix: Converting CO2 Emissions into Sustainable Solar Chemicals & Fuels

by LeeAnne Yu (SCI Innovation) Winner of the 5th China (Shenzhen) Innovation & Entrepreneurship International Competition  --  Bruce Dannenberg founded his company Phytonix in 2009 after having worked in the renewable energy industry for many years. Familiar with a variety

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LanzaTech, with the Support of Danone, Discovers Method to Produce Sustainable PET Bottles from Captured Carbon

(LanzaTech/Globe Newswire) Proof of concept for direct production of monoethylene glycol (MEG), a key building block in sustainable PET production, completed at lab scale -- A consortium, including LanzaTech and Danone, led to the discovery of a new route to monoethylene

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Task Force on Synthetic Biology and the Bioeconomy Releases Landmark U.S. Bioeconomy Report

by Jim Lane (Biofuels Digest)  The Task Force on Synthetic Biology and the Bioeconomy has released its report — THE U.S. BIOECONOMY: CHARTING A COURSE FOR A RESILIENT AND COMPETITIVE FUTURE”. The report contains  recommendations and a strategy to help realize the potential

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Competitive Edge: Codexis, Inc.’s Enzyme Engineering

by Jim Lane (Biofuels Digest)  ... Codexis is a world-leading enzyme engineering company, enabling the promise of synthetic biology across multiple industries – from the sustainable manufacturing of pharmaceuticals, food and industrial products, to the expansion of life science tools and

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SHV Energy and LanzaTech Announce Partnership to Pioneer Renewable Propane

(SHV Energy) SHV Energy and LanzaTech announced a new strategic partnership to employ LanzaTech’s Carbon Capture and Transformation (CCT) technology to bring renewable propane and other sustainable fuels to the market via existing and novel pathways. The collaboration will further expand LanzaTech’s

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Turning Carbon Dioxide into Sustainable Fuel: United and Oxy Low Carbon Ventures Announce Collaboration with Biotech Firm to Create New Fuel Sources

(United Airlines/PR Newswire) Houston-based Cemvita Factory's synthetic biology process has the potential to create a new way to produce sustainable fuel for aviation; United has invested in more SAF production than any other airline --  United Airlines Ventures (UAV) and Oxy

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Six Carbon Capture and Utilisation Technologies for a Sustainable Chemical and Fuel Production Nominated for the Innovation Award “Best CO2 Utilisation 2022”

(nova-Institute)  Carbon Capture and Utilisation (CCU) Innovations of the Year 2022: A lot of technologies are in place and in development to face the challenges of a sustainable chemicals and fuels production based on the utilisation of captured CO2 from industrial off-gases

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Three Partners, Two Problems, One Bioenergy Research Article Published

by Valerie Sarisky-Reed (U.S. Department of Energy)  ... The journal Nature Biotechnology recently published a paper featuring cutting-edge work funded by the U.S. Department of Energy’s Bioenergy Technologies Office (BETO). The article details a carbon-negative platform that uses microorganisms to convert carbon captured

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Converting CO2 to Fuels: The Digest’s 2022 Multi-Slide Guide to Phytonix

by Jim Lane (Biofuels Digest)  Bruce Dannenberg, CEO of Phytonix shared this illuminating slide guide at ABLC Connect highlighting how Phytonix utilizes cyanobacteria engineered via synthetic biology to produce 1-butanol and potentially other higher alcohols. And there’s a sister company,

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ABLC 2022 – State of the Industry

by Helena Tavares Kennedy (Biofuels Digest)  ABLC’s theme of “Dawn of Net Zero” and hundreds of delegates from organizations all over the world grappling with the immense opportunities and supply chain challenges posed by the world’s rapid turn towards charting

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To the (Climate) Rescue: From First Blip in Chromatogram to Deployment at Industrial Pilot Scale

 by Fungmin Eric Liew (Lanza Tech/Nature Bioengineering Community)  Industrial waste gas can serve as feedstock to manufacture fuels and chemicals through gas fermentation. Our work describes a collaborative and multidisciplinary team effort to engineer gas-utilizing microbe to produce acetone and

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Artificial Intelligence Predicts Algae Potential as Alternative Energy Source

by Blair Fannin  (Texas A&M University/AgriLife Today) Jet fuel, animal feed among potential products from algae -- Texas A&M AgriLife Research scientists are using artificial intelligence to set a new world record for producing algae as a reliable, economic source for

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Postdoctoral Researcher Spotlight: Balendra Sah

by Mary Riker (Great Lakes Bioenery Research Center)  ... After I completed my Ph.D., I was looking for a lab where I could do further research in metabolic engineering and synthetic biology, and I found the Landick lab as a suitable

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Synthetic Biology Spotlight: Amyris

by Chris Calvey (National Renewable Energy Lab/Biofuels Digest) ...  Simply put: synthetic biology is a revolutionary new field of science which involves genetically modifying lifeforms – usually simple ones like bacteria or yeast – and redesigning them to do something interesting

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Microbial Production of Fourth-Generation Biofuels

(University of Exeter) Bacteria modified to produce fuel on demand have been produced by University of Exeter researchers in collaboration with energy and petrochemicals group Shell. Academics led by Professor John Love have found a way to get the organisms to produce fuel nearly identical

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Enabling Commercial Success of Industrial Biotechnology

by Bradley W. Biggshal, et al. (Science Magazine)  The industrial biotechnology sector—commercial-scale manufacturing of chemical products by use of cellular or molecular biocatalysts—lies at a crossroads. Metabolic engineering aided by tools of systems and synthetic biology has expanded the scope

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Recycling CO2: The Digest’s 2021 Multi-Slide Guide to LanzaTech

by Jim Lane (Biofuels Digest)  Dr. Sean Simpson, CSO at LanzaTechshared this illuminating slide guide on CO2 pathways to products, how the LanzaJet platform works, how they integrate engineering with biology and AI, why we need to rethink carbon and

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Expanding Molecular Building Blocks: The Digest’s 2021 Multi-Slide Guide to Checkerspot

by Jim Lane (Biofuels Digest) Biological applications could unlockan estimated $2 trillion to $4 trillion in annual direct global economic impact in 10-20 years, said Checkerspot’s CEO and Co-Founder Charles Dimmler at the ABLC in San Francisco. Check out his

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LanzaTech: Radically Rethinking Industrial Business Models

by Erik Kobayashi-Solomon (Forbes) A visit this summer to New Zealand-American synthetic biology company, LanzaTech, opened my eyes to what the term “paradigm shift” means. LanzaTech is an industrial chemicals company that leverages innovations in biology, artificial intelligence, and precision

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Calyxt Expands End Markets for PlantSpring and BioFactory Tech

by Helena Tavares Kennedy (Biofuels Digest) In Minnesota, Calyxt, Inc., a plant-based synthetic biotechnology company, announced a new strategic direction to provide sustainably produced plant-based synthetic biology solutions to an expanded group of end markets and diversified base of customers, leveraging its proprietary

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ADM Further Expands Microbial Science and Technology Innovation Capabilities with Investment in Precision Fermentation Leader Acies Bio

(ADM)  Partnership will help build on ADM’s world-class R&D capabilities and broad portfolio of innovative, responsibly-produced products and solutions  -- ADM (NYSE: ADM), a global leader in nutrition and agricultural origination and processing, announced today that it is making a leading

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SynBio: The Science behind LanzaTech’s Success

by Erik Kobayashi-Solomon (Forbes) As I explained in my first overview article in this series, LanzaTech is an industrial chemicals business. But to describe it as merely another commodity chemicals producer misses the point entirely. At its heart, LanzaTech is a cutting-edge synthetic biology or

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Green Plains, Clean Sugar Tech, BioCampus: The Digest’s 2021 Multi-Slide Guide to Fluid Quip Technologies

by Jim Lane (Biofuels Digest)  You may know Fluid Quip Technologies from their work in ethanol, corn wet milling and biochemical industry, but did you know they have a partnership with Green Plains, BlackRock and others? Get a look at

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Hurry up, Scale up: The Digest’s 2021 Multi-Slide Guide to the U.S. DOE Agile BioFoundry

by Jim Lane (Biofuels Digest)  Enabling biorefineries to achieve 50% reductions in time to bioprocess scale-up, as compared to the current average of 10 years, is what the U.S. Department of Energy aims to do by establishing a distributed Agile

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One-of-a-Kind Course Aims to Build the Bioeconomy Workforce

by Emily Scott (Advanced Biofuels and Bioproducts Process Development Unit) ... He (Jason Ryder, an adjunct professor in UC Berkeley’s College of Chemistry) knows we have the tools to solve these problems: biotechnology and bioprocessing — using the power of

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A Tweaked Yeast Can Make Ethanol from Cornstalks and a Harvest’s Other Leftovers

by Nikk Ogasa (Science News)  The process could tap underused sources of renewable fuels  --  ... But by tweaking a gene in common baker’s yeast, researchers have engineered a strain that can defuse those deadly by-products and get on with the

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The Energy Department Pursues Cleaner and More Efficient Biofuel

by Tom Temin (Federal News Network) One way or another, bio-fuel will be part of the country’s energy future, especially to power ships and airplanes. That’s why the Energy Department’s ARPA-E is spending some $35 million in grant dollars to improve

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I Got 99 Problems but Product vs. Platform Ain’t One: Introducing Microbes-as-a-Service

by Moji Karimi (Cemvita Factory/Biofuels Digest) Any SynBio (synthetic biology) company is faced with three principal questions right off the bat:  1. Product or platform? A) Product: develop the microbe, build the plant, and sell the product. The end molecule is the revenue

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Oxy Low Carbon Ventures, Cemvita Factory Announce Plan to Develop Pilot Plant for Innovative CO2-to-Bio-Ethylene Technology

(Oxy Low Carbon Ventures/PR Newswire)  Oxy Low Carbon Ventures (OLCV), a subsidiary of Occidental (NYSE: OXY), and bio-engineering startup Cemvita Factory today announced a plan to construct and operate a one metric ton per month bio-ethylene pilot plant, applying a jointly developed

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Green Plains Announces Clean Sugar Project in Nebraska

(Green Plains/Ethanol Producer Magazine) Green Plains Inc. and Ospraie Management today announced that recently acquired Fluid Quip Technologies is engineering and constructing a fully scalable commercial Clean Sugar Technology production facility at the Green Plains York Innovation Center. This technology effectively

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The Tri-Fecta – Machine Learning, Synthetic Biology and Automation: The Digest’s 2020 Multi-Slide Guide to Joint BioEnergy Institute

by Jim Lane (Biofuels Digest) Synthetic biology produces fabrics, food, biofuels, health products and more, but we need better predictive power. Machine learning can help and be used to design pathways or choose promoters to optimize production for example. Hector

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Watch: The Role of the Bioeconomy in Ending the COVID-19 Pandemic and Preventing the Next One.

by Luke Upton (BioMarket Insights)  The Global Health Security Seminars from Georgetown University, are looking at some of the biggest challenges that the scientific world is facing, and has recently focussed on this year’s dominant issue – COVID-19. This new era of

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The NEXT 50 Companies to Disrupt the World* (*in a really great way) for 2020

by Jim Lane (Biofuels Digest) In Florida, The Digest announced the NEXT 50, “the 50 Next Companies to Disrupt the World”, for 2020. The NEXT 50 are companies whose emerging technology promises to disrupt markets (or is already doing so) and

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Advanced Fuels Production from Engineered Biology: The Digest’s 2020 Multi-Slide Guide to Seawater-to-Fuels

by Jim Lane (Biofuels Digest)  As part 2 of the seawater-to-fuels discussion from DigestConnect last week, get an insider look at the breakthroughs the U.S. Navy project to produce renewable fuels from seawater using synthetic biology, as shared by Professor

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Fuels from Seawater: The Digest’s 2020 Multi-Slide Guide to Office of Naval Research

by Jim Lane (Biofuels Digest) ... Check out the U.S. Navy’s new gambit and get an inside look at the U.S. Navy’s breakthroughs to produce renewable fuels from seawater using synthetic biology. How does the technology work? What’s the future?

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Movements at Ginkgo BioWorks, Pacific Ethanol, Lygos, LanzaTech Show Where the Bioeconomy Is Heading

by Jim Lane (Biofuels Digest)  So many re-naming and brand extension efforts are underway this week, let’s look at those to see what’s working, what’s popular, when it comes to building trusted brands. ... The Re-Branding: Pacific Ethanol This past week we

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The Digest’s 2020 Multi-Slide Guide to Amyris & Cannabinoids

by Jim Lane (Biofuels Digest)  If you missed Amyris COO Eduardo Alvarez and Sr. VP, R&D Sunil Chandran at last week’s DigestConnect webinar, then check out their slide guide where we asked, is there an opportunity for pure, consistent cannabinoid

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Machine Learning Takes on Synthetic Biology: Algorithms Can Bioengineer Cells for You

by Julie Chao (Berkeley National Laboratory) If you’ve eaten vegan burgers that taste like meat or used synthetic collagen in your beauty routine – both products that are “grown” in the lab – then you’ve benefited from synthetic biology. It’s a field

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NAWCWD, Amyris Collaborate to Develop, Test High-Energy Biosynthetic Fuel

(Naval Air Warfare Center Weapons Division/NAVAIR News) What do bread and liquid jet fuel have in common? Yeast.  At least they can, if you’re talking about the biosynthetic research being done in China Lake, California, by Naval Air Warfare Center Weapons Division and

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New Tech Converts Natural Gas to Hydrogen at Scale Anywhere and Plastic-Eating Enzyme ‘Cocktail’ Heralds Hope for Plastic Waste

by Jim Lane (Biofuels Digest)  ... In today’s Digest, how Florida-based Transform Materials is literally transforming the petrochemical industry’s ability to convert flared natural gas often emitted at hydraulic fracking wellheads into hydrogen and acetylene using microwave plasma technology, and

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LanzaTech Eyes Two More Spin-off Companies

by Kirstin Korosec (TechCrunch) LanzaTech CEO Jennifer Holmgren said Tuesday on the Disrupt 2020 virtual stage that the carbon capture technology company is planning to use its core technology to create two other businesses.  LanzaTech captures waste gas emissions and uses bacteria

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The Rocket’s Glare: Impossible Foods, Moderna, Phillips Are Three Strands of a Single, Driving Braid of Opportunity

by Jim Lane (Biofuels Digest)  ... One of the most astute observers on the energy scene, Tammy Klein, wrote earlier this summer: There has been a high degree of focus by policymakers, the media, NGOs and others on technologies such as

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Follow the Money: The Digest’s 2020 Multi-Slide Guide to Industrial Bioeconomy Revolution

by Jim Lane (Biofuels Digest)  Will Canada transform? Or stand on the sidelines?That’s the question asked by Jeff Passmore, CEO of Passmore Group who shared this illuminating “Follow the Money” slide guide that asks how tenable is fossil fuel’s future?

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Air Force Research Laboratory $1M Synthetic Biology Challenge

(Commercial Aviation Alternative Fuels Initiative) The Air Force Research Laboratory (AFRL) and the Wright Brothers Institute are partnering together to sponsor the second of three $1 million Air Force Challenges. AFRL has been researching the viability of improving performance in composite

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Department of Energy Selects New Projects to Accelerate Innovation and Growth in the Biomanufacturing Sector

(U.S. Department of Energy) Today, the U.S. Department of Energy (DOE) announced the selection of eight projects totaling over $5 million to conduct research and development (R&D) needed to accelerate the US biomanufacturing sector. Part of the Agile BioFoundry (ABF) consortium, these

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The Bio Revolution: Innovations Transforming Economies, Societies, and Our Lives

(McKinsey Global Institute)  Advances in biological sciences, combined with the accelerating development of computing, data processing, and artificial intelligence (AI), are fueling a new wave of innovation that could have significant impact in sectors across the economy, from healthcare and

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Amid Oil Price Crash, a New Hope for Biofuels

by Tina Casey (Triple Pundit)  ... (T)there are reasons to be optimistic about the future of biofuels, as the field continues to evolve remarkably from where it was a decade ago. ... Rather than letting the rest of the plant go to waste, the

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Greenprint for Biomanufacturing and Sustainable Supply Chains: The Digest’s 2020 Multi-Slide Guide to Biostrategy 2020 in a Post-COVID World

by Jim Lane (Biofuels Digest) As biology ravages the global economy, we have a once-in-a-lifetime, trillion-dollar opportunity to help shape how biology will also rebuild it, reports Synbiobeta. We can redefine the economy, supply chains, and manufacturing at local, state, national,

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Silicon-based DNA Synthesis: The Digest’s 2020 Multi-Slide Guide to Twist Bioscience’s DNA Writing

by Jim Lane (Biofuels Digest) DNA is changing the world. That’s what Twist Biosciences is focusing on with synthetic DNA being the future of chemicals, food, therapeutics, diagnostics and even data storage. From next-gen sequencing to synthetic biology, Twist Biosciences envisions a

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Vale Male: Big Changes at the BioEnergy Technologies Office

by Jim Lane (Biofuels Digest)  ... If you’ve noticed that DOE is taking on a much more fundamental bit of science than we’ve seen in the past decade — a move away from catalyzing demonstrations and scale-up and towards more fundamental

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Where Are We? March 2020 Digest Data Dashboard, The Bioeconomy, By the Numbers

by Jim Lane (Biofuels Digest)  The past few weeks have been a roller coaster ride and here are the numbers to visualize what is going on.  In today's Digest, a graphic look at Dow Jones Industrials, biodiesel operating margins, ethanol operating margins,

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How Asia’s Smartest Businessman Plans To Power A Clean Planet With Synthetic Biology

by John Cumbers (Forbes)  ... At the head of Reliance is Mukesh Ambani. As chairman, managing director, and largest shareholder of Reliance, he’s the richest man in Asia, with a reputation as a shrewd investor. He is also a self-described

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Improving Algal Strains with Genomics: The Digest’s 2020 Multi-Slide Guide to Genetic and Synthetic Biology Tools for Algae Productivity

by Jim Lane (Biofuels Digest)  Wild type algal strains don’t have the productivity and robust growth characteristics needed to push algae forward as a biofuel feedstock, but researchers are working on changing that. Stephen Mayfield from the University of California

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Ag-Chemicals, Ag-biologicals, Ag-seeds: The Digest’s 2020 Multi-Slide Guide to Multi-Slide Guide to Evogene’s Artificial Intelligence and Biological Big Data

by Jim Lane (Biofuels Digest) Revolutionizing the product development process in life-science based markets through the use of Computational Predictive Biology platform – sounds like a big mission, but for Evogene, it’s just what they do. They utilize artificial intelligence

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2020 Bioeconomy M&A Deal Review & Outlook

by Jim Lane (Biofuels Digest) The Digest published today a 2020 Deal Review and Outlook Bioeconomy M&A visual guide that looks at the slurry of recent mergers and acquisitions in the bioeconomy like Lygos and Librede, NuSeed and Agrisoma, FinCo Fuels

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#1 Biggest Barrier to Bioeconomy: The Digest’s 2020 Multi-Slide Guide to Bioeconomy Bottlenecks

by Jim Lane (Biofuels Digest)  What are the bottlenecks that prevent technologies from fueling the bioeconomy? Is it government? Is it lack of public acceptance or perception? Is it lack of access to capital? How about lack of market pull?

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The New Carbon Economy: The Digest’s 2020 Multi-Slide Guide to Waste Carbon Utilization and Management

by Jim Lane (Biofuels Digest) Electrification and batteries can’t remove the need for carbon,and a more sustainable economy is not a low-carbon economy as much as it will be a renewable carbon based economy, according to Ian Rowe, Technology Manager at

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Top Industrial Biotechnology Trends in the U.S. – The View from Europe

by Mark Warner (Warner Advisors LLC/Biofuels Digest)  ...   Housed in a region with significant historic chemical operations, including the home of where buna rubber was first commercialized, Eastern Germany is similar to parts of the industrial midwestern United States.  The area

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Cracking the Code of Bacteria: The Digest’s 2019 Multi-Slide Guide to MicroByre’s Engineered Bacteria

by Jim Lane (Biofuels Digest)  “Working with only E.coli is like feeding dogs grass to make milk,” said Dr. Sarah Richardson during this presentation given at ABLC NEXT in San Francisco. With a background in genomes, she shared insight into

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The Digest’s 10 Top Advanced Bioeconomy Markets & Predictions for 2020

by Jim Lane (Biofuels Digest) A mere “The Year in Rewind” as we sail into 2020? Not the good ship Digest! Instead, we dust off our crystal ball and offer our predictions for the year ahead.  As the sunset of 2019 gives

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Methane Bioconversion: The Digest’s 2019 Multi-Slide Guide to iMicrobes’ Methane to Chemicals

by Jim Lane (Biofuels Digest)  Methane is proving to be a pretty valuable waste after all. iMicrobes is using their synthetic biology approach with industrial microorganisms to convert methane into methanol and their first product is 3HP, a key intermediate

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Confessions of a Biorefiner: Green Plains’ Journey into the Land of High-Value Proteins, and the Who, What and Why of That

by Jim Lane (Biofuels Digest) This week news came out of a partnership between Novozymes and Green Plains to use biological technology to extract more value from corn protein, at what used to be known as corn ethanol plants, but with

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Conversion Technologies: The Digest’s 2019 Multi-Slide Guide to BETO’s Carbon-Based Fuels and Co-Products

by Jim Lane (Biofuels Digest)  Why is working with biomass so challenging? Jonathan Male, Director at the U.S. Department of Energy’s Bioenergy Technologies Office (BETO) set out to answer that question at ABLC NEXT in San Francisco. Check out his illuminating

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Simplifying Biology for Biochemicals: The Digest’s 2019 Multi-Slide Guide to DMC’s Metabolic Engineering Tech

by Jim Lane (Biofuels Digest)  ... Digital biology, synthetic biology and metabolic engineering are not all the same – just ask Matt Lipscomb, CEO and Founder of DMC who shared this presentation at ABLC NEXT in San Francisco. Check out

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Cemvita Factory Rockin’ It: The Digest’s 2019 Multi-Slide Guide to Cemvita’s CO2 Utilization

by Jim Lane (Biofuels Digest)  Earlier this week we talked about making protein and meat out of air, so taking CO2 and utilizing it seems right in line. C+C Music Factory’s song from the early 90’s “Everybody Dance Now” comes to

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Exclusive Expert Insights from Day One and Day Two of SynBio Markets 2019.

by Liz Gyekye (BioMarket Insights)  ...  Another era has started today with the launch of Bio Market Insight’s first SynBio Markets conference, which has kicked off with a bang. Set in the quirky ewerk location in Berlin, Germany, industry heavyweights have taken part in keynotes, 

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The Magic behind the Molecules and Materials: The Digest’s 2019 Multi-Slide Guide to Checkerspot’s Synthetic Biology

by Jim Lane (Biofuels Digest) “The measure of how disruptive Synthetic Biology is lies in the applications, the use cases and relevance to consumers,”according to Checkerspot which uses biology and chemistry to generate novel building blocks. Their ingredients include custom oils

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Oh So Sweet! Amyris’s Look at Farnesene Production from Sugars: The Digest’s 2019 Multi-Slide Guide to MegaBio and Farnesene

by Jim Lane (Biofuels Digest)  Amyris is working on a MegaBio goal. Mega because it’s a big goal – develop a fully integrated and scalable process to produce farnesene from cellulosic sugars at $2 per liter in the U.S. Quinn Mitrovich from Amyris

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Catch & Kill: The Velocys, Oxy, Cemvita, Carbon Engineering, BHP, Ginkgo Chase to Catch Waste, Kill Emissions, Armed with New Organisms to Liberate Value

by Jim Lane (Biofuels Digest)  In Mississippi, Velocys’ Bayou Fuels project has signed with Oxy Low Carbon Ventures to capture carbon dioxide from Velocys’ planned Bayou Fuels biomass-to-fuels project in Natchez, Mississippi, and securely store it underground in a geologic

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Investing in Australian Biomanufacturing

(Office of the Department  of Education; the Hon Dan Tehan MP, Minister for Education; the Hon Karen Andrews MP Minister for Industry, Science and Technology; John Alexander OAM, MP, Member for Bennelong ) The Morrison Government is investing in the development of

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Synthetic Fuels Could Shrink Carbon Footprint

by Vicky Just (University of Bath/Phys.org)  Synthetic fuels, made using carbon captured from the air, farm waste or biomass, could help the transport sector reduce its reliance on fossil fuels and meet "net-zero" greenhouse gas emission goals. A policy briefing by the

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The NEXT 50 Companies to Disrupt the World

by Jim Lane (Biofuels Digest) In Florida, The Digest recognized the NEXT 50, “the 50 Next Companies to Disrupt the World”, bioeconomy companies that are just now reaching commercial scale with an emerging technology, or earlier in their journey to commercial

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Replacing the Barrel: The Digest’s 2019 Multi-Slide Guide to Conversion Technologies

by Jim Lane (Biofuels Digest) Developing efficient and economical biological and chemical technologies to convert biomass feedstocks into energy-dense liquid transportation fuels, such as renewable gasoline, diesel, and jet fuel, as well as bioproducts, chemical intermediates, and biopower is the primary goal

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EUSynBioS Symposium --- September 30-October 1, 2019 --- Brno, Czech Republic

The fourth EUSynBioS Symposium is coming this year to the rising biotech hub Brno in the Czech Republic, bringing together the young European synthetic biology community. Together with the Biomania student association the symposium will take place from the 30th

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How Synthetic Biology Can Help Build Sustainable Cities

by John Cumbers (Green Biz/SynBioBeta)  Sustainability is in vogue, with businesses and cities jostling to improve their public image and produce goods and services using renewable sources. Yet cities exponentially swell and carbon emissions continue to increase. Global CO2 emissions rise

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Hong Kong University of Science and Technology Receives Gift of HK$500m to Set up Synthetic Biology Institute.

by Liz Gyekye (BioMarket Insights) “It is fascinating that a humble yeast is the superstar of the next industrial revolution.”  --  Hong Kong-based plastics and real estate mogul Li Ka-Shing has announced a donation of HK$500 million (USD$64 million), via his Li

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The Advanced Bioeconomy Report Q2 2019 Earnings: The Year of Living Endangeredly

by Jim Lane (Biofuels Digest) In hand we now have the latest earnings reports from what you might call the 8 Pathfinders – eight publicly traded stocks whose second quarter results offer insights into the health and performance of the advanced

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Tulane Researcher Working to Turn Waste to Fuel Wins NSF Career Award

by Barri Bronston  (Tulane University)  Nicholas Sandoval's lab at Tulane works on the development and application of advanced synthetic biology tools for microbes and other model cell lines for the purpose of therapeutics and sustainable fuel and chemical production. -- Nicholas

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Biomanufacturing 2.0 Cell-Free: The Digest’s 2019 Multi-Slide Guide to Invizyne Technologies

by Jim Lane (Biofuels Digest) Invizyne Technologies is making chemicals the cell-free way using synthetic biology and metabolic engineering. By inputting sugar and using engineered microbes, they can result in useful compounds and commodity chemicals, biofuels, fuel additives, fragrances, and pharmaceuticals. James

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Demise of the Diva: The New Organisms Are Workhorses Not Show Ponies, but They Do the Most Amazing Tricks.

by Jim Lane (Biofuels Digest) ... What we would like to train our focus on is two-fold, the advances in systems biology — elsewhere, you’ve heard it described as synthetic biology, but it’s really all a part of systems biology, which

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Algae and Synthetic Ecology: The Digest’s 2019 Multi-Slide Guide to New Mexico Consortium

by Jim Lane (Biofuels Digest)  New Mexico Consortium is non-profit corporation formed by 3 NM universities to facilitate research collaborations for universities, industry & Los Alamos Laboratory. They are looking to algae as a solution where cell factories could produce energy

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Power of Biology for Algae Biofuels: The Digest’s 2019 Multi-Slide Guide to Synthetic Genomics

by Jim Lane (Biofuels Digest)  Synthetic Genomics is a San Diego biotechnology company harnessing the power of living cells — nature’s most efficient machines — to create transformative medicines and bio-based products. Their teams of data and biological engineers have developed the

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ABLC 2019 Round-Up

by Helena Tavares Kennedy (Biofuels Digest)  ... ABLC 2019 kicked off on Wednesday with about 540 delegates in Washington, D.C. at the U.S. Department of Agriculture building complete with secret service protection and escorts for some big-name super star speakers, with

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Methane to Chemicals: The Digest’s 2019 Multi-Slide Guide to iMicrobes

by Jim Lane (Biofuels Digest) Industrial Microbesupgrades methane to various multi-carbon chemicals using synthetic biology. Noah Helman, CSO and Co-Founder of iMicrobes gave this illuminating overview of methane as a feedstock, the breakthrough in active MMO in E.coli that has allowed easier methane

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Harnessing Synthetic Biology to Co-Produce High-Value Terpenoid Biomaterials and Biofuel in Plants

(Michigan State University/Phys.Org)  Michigan State University scientists have developed synthetic biology tools to co-produce high-value compounds in plants. The study is published today in the journal Nature Communications. Terpenoids form the largest class of natural products in plants and have been used

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Scale-Up From the Microbes Perspective

by Mark Warner (Warner Advisors LLC/Biofuels Digest)  On a biotechnology project years ago, one of the team members responsible for biological advancement referred to themselves as the microbial organisms “shop steward”, a reference to union representation.  While it was somewhat in jest,

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Expanded Centre for Synthetic Biology Launches at Imperial

by Hayley Dunning (Imperial College London)  The Centre brings together researchers using synthetic biology to solve challenges such as in healthcare, biomaterials and sustainable energy. Synthetic biology is the application of engineering principles to biology; designing and creating biological components and systems

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Tapping the Genetic Power of Algae: The Digest’s 2018 Multi-Slide Guide to Algenol

by Jim Lane (Biofuels Digest)  Algenol is a global, industrial biotechnology company that is commercializing its patented algae technology platform for production of ethanol and other biofuels, chemicals and biobased materials. Formed in 2006, and headquartered in Fort Myers, Florida with an

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New Report on Cell-Free Synthetic Biology and Biocatalysis!

(U.S. Department of Energy)  Cell-Free Synthetic Biology and Biocatalysis Listening Day Summary Report Published   --  The U.S. Department of Energy's (DOE’s) Bioenergy Technologies Office (BETO) hosted a listening day in Denver, Colorado, last year to discuss research and development opportunities related to

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Redesigning Poplar Trees to Take the Drought ... and the Salt and the Heat

by Laura Shields  (Environmental Molecular Sciences Laboratory/Pacific Northwest National Laboratory)  Improving poplar biomass production under stress conditions --  ... Stresses, such as high temperatures and a lack of freshwater, can cause reduced crop growth or even complete loss. The rising frequency of these

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Industrially Important Molecules: The Digest’s 2018 Multi-Slide Guide to Constructive Biology

by Jim Lane (Biofuels Digest)  Berkeley legend Jay Keasling gave this illuminating overview of the promise and progress of a new company in the Keasling universe, Constructive Biology. READ MORE

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New Synthetic Biology Initiative to Boost Bio-Economy

(University of Queensland)  A $4.5 million initiative to boost Australia’s synthetic biology capabilities will be built by The University of Queensland and CSIRO, helping drive advances in areas such as manufacturing, industrial biotechnology, environmental remediation, biosecurity, agriculture and healthcare research. UQ

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Proteins and Synthetic Biology: The Digest’s 2018 Multi-Slide Guide to Codexis

by Jim Lane (Biofuels Digest)  Codexis is a leading protein engineering company that applies its technology to the development of biocatalysts for the commercial manufacture of pharmaceuticals and fine chemicals. Codexis’ proven technology enables implementation of biocatalytic solutions to meet customer

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Closing the Applications Gap: Checkerspot Closes $5M Seed Financing in Pursuit of High-Performance Biomaterials

by Jim Lane (Biofuels Digest)  ... (C)onsider this venture about Making the Right Stuff — that is, how you translate an entire generation of innovation in digital biology, biobased chemical engineering and advanced fabrication into actual stuff. Or, how you

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Hot Tech for Fuels: The Digest’s 2018 Multi-Slide Guide to the Joint BioEnergy Institute

by Jim Lane (Biofuels Digest)  JBEI’s mission is to convert biomass to biofuels. The goal is to provide the nation with clean, renewable transportation fuels identical to gasoline, diesel and jet fuel. Inside JBEI’s Emeryville laboratories, researchers are using the latest tools

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The Scientist Still Fighting for the Clean Fuel the World Forgot

by James Temple (MIT Technology Review)  In the closing weeks of 2008, the US Department of Energy invited politicians and press to a dedication ceremony for the Joint BioEnergy Institute in Emeryville, California. The state-of-the-art lab, backed by $125 million in

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The Digest’s 2018 Multi-Slide Guide to the Biorefinery of the Future

by Jim Lane (Biofuels Digest) What will biorefineries look like, accomplish and cost in the future? Daniel Lane of Saille Consulting and Lee Enterprises Consulting looked at that topic in this illuminating overview of the promise and prospects for the technological

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‘Augmented Biology’: Exploring New Avenues in Biofuel Production

(University of Bristol)  Researchers in the Schools of Biochemistry and Chemistry are working to boost cellular productivity of biofuels at a fundamentally scientific level in order to create innovative, sustainable solutions to our global energy needs. ... Collaborating with scientists from the University

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The Digest’s Top 10 Innovations, 3.28.18 Release

by Jim Lane (Biofuels Digest)  According to BIO, the global economic value today of the biobased economy – including industrial biotechnology, renewable chemicals and polymers, biofuels, enzymes and biobased materials – is $355.28 billion. And looking at the new USDA Indicators report

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Biorefineries: Our Synthetic Biology Future

by Bob Kodrzycki (Encompass Biotech LLC/Lee Enterprises Consulting/Biofuels Digest)  ... Opportunity, such as the availability of a new feedstock or the possibility of combining technologies can lead to very interesting outcomes. ...  Technology alone is usually not enough to develop a market. But combined

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Innovators Dilemma Revisited in Renewable Chemicals and Materials

by Daniel Lane and Joel Stone (Lee Enterprises Consulting, Inc./Biofuels Digest)  ... These disruptive technology innovations have happened many times throughout history and are discussed in the popular book The Innovator’s Dilemma, by Clayton Christensen. He coined the phrase in describing a process

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State of the Advanced Bioeconomy 2018 – An 8-Part Series

by Jim Lane (Biofuels Digest)  This week in the Digest, we begin a Special 8-part Series: The State of the Advanced Bioeconomy: Challenges and Priorities for 2018. As we head into the final month before ABLC 2018, these in-depth examinations from a group

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The 12: The Advanced Bioeconomy’s 12 Biggest Talking, Fretting, Praying and Action Points Right Now

by Jim Lane (Biofuels Digest)  ... What are the top trends? Here are the 11 we see dominating the debate on the stage and on the floor. Jet fuel deployment – how much, how soon, by whom? California, look up, not down! 

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This Is an Algorithm, That Is Alive: The Rise of Arzeda and Digital Biology

by Jim Lane (Biofuels Digest)  The question is being raised all over Silicon Valley — and increasingly around the world — if biotechnology is essentially a branch of information technology.  ... Investors, theorists, entrepreneurs are forming a thesis that profound improvements in the physical world

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Synthetic Biology-enabled Manufacturing: The Digest’s 2017 Multi-Slide Guide to Visolis

by Jim Lane (Biofuels Digest)  The Visolis process will enable production of bio-based elastomers, unsaturated polyester resins, super adsorbent polymers, and other products using a variety of feedstocks like agri-residues, dextrose, glycerol and syn-gas. As we come down the cost curve,

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SimPath Licenses Novel ORNL System for Enhanced Synthetic Biology

(Oak Ridge National Laboratory)  SimPath has licensed a novel cloning system developed by the Department of Energy’s Oak Ridge National Laboratory that generates and assembles the biological building blocks necessary to synthetically bioengineer new medicines and fuels. Knoxville, Tennessee-based startup SimPath

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Productionizing Synthetic Biology: The Digest’s 2017 Multi-Slide Guide to the Agile BioFoundry

by Jim Lane (Biofuels Digest) The Agile BioFoundry, designed to productionize synthetic biology, is a public infrastructure investment aimed at increasing U.S. industrial competitiveness and enables new opportunities for private sector growth and jobs. Specifically, the foundry aims to enable a biorefinery

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N-butanol and Beyond: The Digest’s 2017 Multi-Slide Guide to Green Biologics

by Jim Lane (Biofuels Digest)  Green Biologics is focused on the production of renewable n-butanol and other C4 chemicals from various renewable feedstocks, including sugar (cane, molasses, beets), starch (corn) and cellulosic biomass (corn residues, sugar cane bagasse, forest materials

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Protein, Pathway Design: The Digest’s 2017 Multi-Slide Guide to Arzeda

by Jim Lane (Biofuels Digest)  Arzeda’s proprietary technology combines targeted computational enzyme design and protein optimization with state-of-the-art metabolic bioengineering to create entirely novel designer cell factories capable of industry-scale chemical production. CEO Alex Zanghellini gave this illuminating overview of Arzeda’s breakthrough technology at ABLC 2017 in

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New Capabilities for Genome-Wide Engineering of Yeast

by Claudia Lutz (Chemical and Biomolecular Engineering at Illinois)  New approach combines synthetic biology, genome editing tools, and automation to quickly and effectively produce novel yeast strains One of humankind’s oldest industrial partners is yeast, a familiar microbe that enabled early societies

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Little Big Ally: The Digest’s 2017 Multi-Slide Guide to Ginkgo BioWorks

by Jim Lane (Biofuels Digest)  Ginkgo Bioworks designs custom microbes for customers across multiple markets. We build our foundries to scale the process of organism engineering using software and hardware automation. Organism engineers at Ginkgo learn from nature to develop

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1 Septillion Reasons Dad’s CRISPR-Cas9 May Already Be Toast

by Jim Lane (Biofuels Digest)  ... CRISPR-Cas9 is a technique for making a cut at a desired point in a cell’s genome. You can pick the spot and do an edit. Amazing stuff. You can clip out junk genes, or

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CHASSY – New EU Yeast Biotech Project

(CHASSY)  ... Yeast is already the powerhouse behind many food flavourings, the anti-aging compound Resveratrol, the malaria drug Artemisinin, the grapefruit extract Nootkatone, insulin, bioethanol, bioplastics, and there is potential for many more industrial applications. To better exploit the potential of yeast

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Textbook: Biofuels and Bioenergy

edited by John Love and John A.  Bryant (Wiley-Blackwell)  With increased public and scientific attention driven by factors such as oil price spikes, the need for increased energy security, and concerns over greenhouse gas emissions from fossil fuels, the production

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Gigabase Is the New Megabase: The Digest’s 2017 Multi-Slide Guide to Gen9

by Jim Lane (Biofuels Digest)  The company manufactures custom, high-quality, synthetic DNA used by scientists to construct genes, pathways, genomes and organisms that will enable the next generation of breakthroughs in biology. Word came through this week that Gingko BioWorks

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thermocellum cloud point clover cmelina CNG Conversion kit co co-generation co-location Co-op Extension co-operative co-processing co-products CO2 Electrolysis CO2 neutral fuels CO2Removal Certificates (CORCs) coal Coal and Biomass to Liquid (CBTL) Coast Guard coastal habitat conservation coastal hay cobalt cock's foot coco coco methyl ester (CME) cocoa Coconut coffee coffee cherries coffee grounds coffee pulp cold flow cold-tolerance college/university Colombia Colorado combined heat and power (CHP) Comment Request commercial flights commercialization commissioning commo Commodity Credit Corporation (CCC) Commodity Futures Trading Commission (CFTC) commodity trading common reed Community activity community college Community involvement/engagement community scale Community Wood Energy Program competition compliance compliance credits compost Compressed Natural Gas (CNG/R-CNG/bioCNG) compression ratios compression-ignition engine computer simulation concrete condensate Congo Congressional Budget Office (CBO) Connecticut Conservation Reserve Program (CRP) Conservation Stewardship Program (CSP) construction and demolition waste/debris consumer education contamination contest contrails conversion technology Cook Islands cook stoves cooking fuel cooperatives COP21 COP22 COP23 COP24 COP25 COP26 COP27 COP28 COP29 COP30 copper coppice cordgrass corn bran Corn cobs corn ethanol corn fiber corn growers corn harvest corn kernel corn meal corn oil corn oil/distillers corn oil (DCO) corn prices corn stalks corn stover corn supply corn surplus corn syrup corn-based products corn/maize Corporate Average Fuel Economy (CAFE) standards corporate social responsibility corrosion corruption CORSIA (Carbon Offsetting and Reduction Scheme for International Aviation) cosmetics Costa Rica cotton cotton seed hulls cotton seed oil cotton stalk cottonwood Council on Environmental Quality county cover crops cow rumen cracking Crambe crassulacean acid metabolism plants (CAM) crimes criteria pollutants Croatia crop crop insurance cropland croton crowdfunding crude oil Cuba cup plant cuphea currency/foreign exchange policy curriculum cusi cutworm caterpillars cyanobacteria (blue-green algae) cylindro Cyprus Czech Republic d D-3 (cellulosic) RINs D-4 (bio-based diesel) RINs d-5 D-5 (advanced biofuel) RINs D-6 (renewable fuel) RINs D-7 RINs (Cellulosic Diesel) D-8 (proposed) RINs D20 (20%DME) D5 (5%DME) dairy waste dandelion DARPA date kernel oil date palm date palm pits date palm waste Dates DDGS (distiller’s dried grains with solubles) dead zone decanol decision-support tool deep water drilling Defense Logistics Agency (DLA) Defense Production Act deficit definitions deforestation defossilization Dehydration Delaware DeltaWing demonstration demonstration scale/unit Denmark densify density Department of Agriculture (USDA) Department of Commerce Department of Defense (DOD) Department of Education Department of Energy (DOE) Department of Health and Human Services Department of Homeland Security Department of Justice Department of Labor Department of the Interior Department of Transportation (DOT) depolymerization depots dextrose dfdsffsfdfsf diatoms diesel Diesel Emissions Reduction Act (DERA) diesel fuel blendstock diesel prices Diesel R5 diesel with renewables diesel-range hydrocarbons diesel-to-biodiesel conversion diethyl ether digital Digital Biology diisobutylene (DIB) dilute acid hydrolysis pretreatment DIN 51605 DIN EN 15376 (Ethanol blending component) direct air capture direct injection direct ocean capture Direct Sugar to Hydrocarbon Conversion (DSHC) direct-to-fuel directed evolution dispense distillates distillation distilled biodiesel distilled palm methyl ester (DPME) distilleries distributed/centralized distribution distribution capacity distribution waiver diversification divestment DME/rDME (dimethyl ether)/renewable DME DMF (2.5-dimethylfuran) Dominican Republic double cropping drawdown Drones/Unmanned Aerial Vehicles (UAV) drop-in biofuels/hydrocarbons drought drought tolerant drought-resistant dry ice dual cropping Dubai duckweed e e-diesel e-LNG (synthetic/electro Liquified Natural Gas) e-methanol e-NG (synthetic natural gas) E. coli E0 E0 price E1 E10 E10 certification fuel E10 price E100 E100 conversion kit E11 E12 E13 E15 E15 price E15 pumps E2 E20 E20 price E20 pumps E22 E25 E25 pumps E27 E3 E30 E30 capable E30 certification fuel E30 optimized E30 price E30 pumps E35 E4 E40 E40 conversion kit E40 pumps E5 E5 price E50 E55 E6 E7 E70 diesel E75 E78 E8 E80 E85 E85 conversion kit E85 optimized engines E85 price E85 pumps E90 E92 E95 E97 E98 earthquakes East Africa Eastern Europe economic development Economic Development Administration economic modeling economic policy economics Ecosystems Services Ecuador ED7 (7% ethanol 93% diesel) ED95 education Education Series 3030 educational business private educational tour EERE efficiency egg shell Egypt El Salvador Electric aircraft Electric Car/Electric Vehicle (EV) electric car/Electric Vehicle (EV) Prices electric grid electricity electricity price electricity/power generation electricity/power transmission electrocatalysis electrochemical electrochemical cell electrofuels (e-fuels) electrofuels (e-fuels) prices electrolysis electrolytic cation exchange electromethanogenesis (ME) electrons Elephant grass/Napier grass elephants embargo eminent domain emissions emissions standards EN 15751 EN 15940 EN 16709 EN 228 EN 590 EN228 (standard pump gasoline) end user end-of-life Endangered Species Act (ESA) Energy Bill energy cane energy consumption energy crops energy density energy dominance energy grasses energy independence Energy Independence and Security Act of 2007 (EISA) Energy Information Administration (US EIA) energy law energy policy energy prices energy reserves Energy Return on Energy Invested (EROEI or EROI) energy security Energy Security Trust energy storage enforcement engine Engine Development engine problems Engine/Fuel Co-optimization engineering England enhanced oil recovery (EOR) entrepreneur environment environmental impact study (EIS) environmental justice/socially inclusive environmental policy Environmental Quality Incentive Program (EQIP) Environmentalists Enzymatic enzymatic conversion enzymatic depolymerization enzymatic hydrolysis enzyme production enzyme recycling Enzyme solicitation enzymes EPA (Environmental Protection Agency) EPACT (Energy Policy Act) Equatorial Guinea equipment eRINs/electric pathway Eritrea erosion control EROWI (Energy Return on Water Invested) ESG (Environmental Social Governance) esterification Estonia ETBE (ethyl tert-butyl ether) etha ethane ethanol ethanol benefits ethanol blend wall ethanol blended diesel ED ethanol blends/ethanol flex fuels ethanol emissions ethanol ether diesel fuel ethanol fire ethanol fuel cells ethanol hybrid ethanol pipeline ethanol prices ethanol production ethanol pumps ethanol tax ethanol terminal ethanol to gas ethanol tolerance ethanol-fueled aircraft Ethanol-to-Gasoline (ETG) ethanol/bioethanol ethanol/diesel ethanol/methanol synthesis ethanol2G Ethiopia Ethiopian mustard ethyl levulinate (EL) ethylbenzene ethylene ets eucalyptus Euglena European Emissions Trading System (ETS) European Union (EU) eutrophication executive order executive order--state Extended Range Electric Vehicle (EREV) externalities extremophiles f F Factor F-24 F-34 F-76 (Marine Diesel) F-T FAEE FAEE (fatty acid ethyl esters) Fair trade False Claims Act FAME (Fatty Acid Methyl Ester) Farm Bill Farm Bureau farm equipment farm policy Farm to Fleet Farm to Fly farmers farming farnesane farnesene Fats fecal sludge Federal Aviation Administration (FAA) Federal Bureau of Investigation (FBI) Federal Emergency Management Agency (FEMA) Federal Energy Regulatory Commission (FERC) Federal Highway Administration (FHWA) federal land Federal Railroad Administration Federal Reserve Bank Federal Trade Commission (FTC) Federal Transit Administration (FTA) feed Feed In Tariffs (FIT) feed prices Feedstock Flexibility Program for Bioenergy Producers feedstock logistics feedstock material feedstock prices feedstock storage feedstock terminal feedstock transportation Feedstocks fermentation ferry fertilizer fiber Fiji Financing Finland Fischer-Tropsch Synthetic Kerosene with Aromatics (FT-SKA) Fischer-Tropsch Synthetic Paraffinic Kerosene (FT-SPK) Fischer-Tropsch Synthetic Paraffinic Kerosene with Aromatics (FT-SPK/A) Fischer-Tropsch/FT fish feed fish oil fish waste fit for purpose Fixed Base Operator (FBO) flameleaf sumac flavors flax fleet turnover Fleets fleshings flex-fuel vehicles (FFV) flight tests Flightpath flixweed/tansy/herb-Sophia flood-prone soil Florida flue gas FOG (Fats/Oils/Grease) follow-the-crop food Food and Agriculture Organisation (FAO) Food and Drug Administration (FDA) food and fuel food policy food prices food processing waste food safety food security food vs biomaterials/bioplastics food vs fuel food waste for forage forage sorghum forecasts foreign oil Foreign Policy forest Forest Biomass for Energy forest biotechnology forest residue/waste Forest resources Forest Service forestry forklifts Formate formic acid fossil carbon fossil fuel Frace fracking fractionation fragrance France franchise fraud free fatty acids (FFA) Freedom of Information Act (FOIA) freight/cargo French French Guiana fructose fruit FT-SKA fuel fuel additives fuel cell electric vehicle (FCEV) fuel cells fuel economy fuel efficiency fuel injection fuel mixtures fuel molecules fuel oil fuel performance fuel prices Fuel Quality Directive (FQD) fuel registration Fuel Retailers fuel testing fuel transportation fuel use fuel wholesaler fully burdened cost fund funding fungus/fungi Furanics furfural fusel oils Future Farmers of America (FFA) Gabon gallium Gambia games gas prices gas tax/highway user fee gas-to-liquid (GTL) gasification gasoline gasoline baseline gasoline consumption gasoline mandate gasoline markets gasoline price gasoline-range hydrocarbons Gemany General Services Administration general waiver authority generators genetically engineered yeast cells genetically enhanced microbes genetically modified organism (GMO) genome Georgia Georgia (country) geothermal German Germany Gerrmany Ghana GHG (Greenhouse Gas Emissions) GHG (Greenhouse Gas Emissions) Intensity giant cane giant kelp Giant King Grass Giant Reed/Arundo GIS glass tubing gliricidia sepium global rebound effect Global South global warming global warming potential glucose glycerin glycerin standards glycerol goats gorse Governance practices) Government Accountability Office (GAO) government investment government resources government subsidies grain sorghum/milo grain speculators grains GRAND-AM grants grants-local grants-state grapefruit grapes graphene graphite GRAS (generally regarded as safe) Grasses grasses grasshoppers grease Great Green Fleet Great Lakes Greece green bonds green chemistry Green Deal EU green economy green house facility Green Jobs Green New Deal Green Racing Green Recovery green/black economy Greenland GREET Greenhouse Gases Regulated Emissions and Energy Use in Transportation Model Grenada gribble growers gua beans Guam guar Guatemala guayule Guerbet reaction Guinea Guinea Bissau Gulf states gulmohar Gumweed (grindelia squarosa) Guyana GWP gypsum h Haiti Halophytes harvest site processing harvesting Hawai'i hay hazardous waste hazelnut HBIIP Higher Blends Infrastructure Incentive Program HDCJ HDO-SAK (hydro deoxygenated synthetic aromatic kerosene) health health benefits health effects heat of combustion heat of vaporization heat-tolerance heather heating oil/fuel Heavy Duty Truck Rule heavy duty vehicles (HDV) hedging HEFA (Hydro-processed esters and fatty acids) HEFA50 helicopters hemicellulace enzymes hemicellulose hemicellulosic sugars Hemp hemp oil hemp seed herb hexanol HFO (Heavy Residual Fuel Oil) hibiscus high blend renewable fuels (HBRF) High Hydrogen Content Synthetic Paraffinic Kerosene (HHC-SPK) High Octane Fuel (HOF) High Octane Fuel Standard High Octane Gasoline (HOG) high octane low carbon (HOLC) fuel High Octane Vehicles (HOV) high performance regular high school project high sulphur fuel oil (HSFO) high-octane/low-carbon (HOLC) liquid fuels Highway Bill highway rights-of-way Highway Trust Fund history hog farmers hombayniya homogeneous-charge compression-ignition Honduras honey locust Hong Kong Honge tree nuts hops horticulture Housing and Urban Development (HUD) HPF (High Performance Fuels) HRJ (Hydrotreated Renewable Jet) human rights Hungary Hurricane Sandy HVO (Hydrotreated vegetable oil) HVO100 HVO20 HVO30 Hybrid aircraft hybrid buses hybrid locomotive hybrid ships hybrids hydrocarbon fuels Hydrocarbon-Hydroprocesed Esters and Fatty Acids (HC-HEFA-SPK) hydrodeoxygenation hydrodiesel hydrofaction hydroformylation hydrogen aircraft hydrogen carrier hydrogen combustion engines hydrogen fuel cells hydrogen leaks hydrogen pipeline hydrogen price hydrogen pumps/fueling stations hydrogen tax credit hydrogen terminal Hydrogen/Renewable Hydrogen Hydrogen/Renewable Hydrogen Price hydrogenase hydrogenation hydrogenation-derived renewable diesel (HDRD) hydrogenolysis hydropower Hydroprocessed fermented sugars to synthetic isoparaffins (HFS-SIP) hydroprocessing hydropyrolysis hydrothermal carbonization hydrothermal gasification hydrothermal liquefaction (HTL) hydrothermal treatment Hydrotreated renewable diesel (HRD) hydrotreating hydrotreatment hydrous ethanol hypoxia zone Iceland Idaho Illinois Illiois illuppai ILUC (Indirect/Induced Land Use Change) import/export incinerator ash India Indian beech tree Indian grass Indiana indirect effects indirect emissions indirect fuel use change indium Indonesia industrial burners industrial ethanol industrial gases industrial sugars industrial waste industrial waste gases IndyCar infographic Infrastructure inhibitors innovation insecticide/pesticide insects insurance integrated biorefineries integrated food/energy systems intellectual property Inter-American Development Bank inter-crop interactive map intercropping internal combustion engine (ICE) internal combustion engine (ICE)/gasoline engine ban International international balance of payments International Council on Clean Transportation (ICCT) International Energy Agency (IEA) International Maritime Organization (IMO) International Monetary Fund (IMF) International Organization for Standardization (ISO) International Renewable Energy Agency (IRENA) International Sustainability and Carbon Certification model(ISCC) International Trade International Trade Administration International Trade Commission Internships inulin invasive species Investing investment tax credit Invvesting ionic liquids Iowa IPCC Intergovernmental Panel on Climate Change Iran Iraq Ireland iridium iron iron oxide IRS (Internal Revenue Service) IS 1460 ISO 8217 (marine distillate fuel standard) ISO 9000 isobutanol isobutanol price isobutanol pump price isobutene isobutylene isomerisation isooctane isooctene isopropanol Israel Italy Ivory Coast JAA jackfruit Jamaica jamelão Japan jatobá Jatropha Jersey Jerusalem artichoke jet jet A Jet A-1 jet B Jetfuel (Sustainable Aviation Fuel (SAF)) Jimmy Carter Jobs Joint Office of Energy and Transportation jojoba Jordan JP-10 JP-4 JP-5/NATO F-44 JP-8/NATO F-34 juniper Just A MInute Just Transition jute K-12 Education Kabakanjagala kalanchoe kamani Kans grass Kansas Karanja Kazakhstan kelp Kemiri Sunan kenaf Kentucky Kenya kerosene ketones kinggrass Kiribati knotweed Knowledge Discovery Framework Korea Kosovo kudzu kukui nut kulpa kusum Kuwait Kygryzstan labels labor policy Labrador lactic acid lactose Lake County lamp oil land ownership land prices land rights land subsidence land tenure land transfer land use land use change land use policy landfill methane Landfills landscape Laos Latin America Latvia LCFS (Low Carbon Fuel Standard) lead Leadtree leaf ant Lebanon lecithin legislation Legislation-Federal Legislation-State lemna lend-lease Lesotho lesquerella leucaena levulinic acid Liberia Libya licensing lichens life cycle analysis (LCA) light rail lignin Lignin Ethanol Oil (LEO) Lignocellulosic Biofuel lignocellulosic sugars lime Lipid liquefaction liquid liquid petroleum gas (LPG) liquid transportation fuels liquidation Liquified Biogas (LBG) Liquified Biogas (LBG) pumps liquified biomethane (LBM) Liquified Natural Gas (LNG) lithium Lithuania litigation Litigation-Federal Litigation-State livestock loan guarantees loans lobbying loblolly pine locomotives lodgepole pine logistics long-term contracts Louis Louisiana low c low carbon emissions low carbon octane standard (LCOS) Low Emission Vehicle Standards (LEV) low sulfur diesel low sulfur fuel low sulfur marine fuel lubricants lumber mill Luxembourg lysis M100 M15 M3 M50 ma macadamia macauba Macedonia machine learning machinery macororo Madagascar magnesium mahua Maine Malawi Malaysia Maldives Mali 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microbial electrosynthesis microbiology microorganisms/microbes microwave Mid-Atlantic Middle East Midwest mileage military military policy military reserves military specifications military strategic flexibility military strategy military use of biofuels milk permeate millennium fruit millet millettia pinnata milo stover mineralization minerals mining Minn Minnesota miscanthus misfueling missile fuel Mississippi Missouri mixed prarie mobile refinery modeling modular molasses mold molinia molybdenum MON (Motor Octane Number) Monaco Mongolia mongongo monitoring/measuring reporting verifiction (MRV) Montana Montenegro moose morama Moringa tree Morocco morula motorcycles motors MOVES (motor vehicle emissions simulator) modeling system MOVES2014 MOVES3 (MOtor Vehicle Emission Simulator model) Mozambique MSW (Municipal Solid Waste) MTBE (Methyl tert-butyl ether) multi-fuel municipal/city mushroom mushroom substrate mustard seed mvr Myanmar n-butanol n-butene nahar Namibia nano nano 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energy balance Netherlands Nevada New Brunswick new fuel approval New Guinea New Hampshire New Jersey New Mexico New South Wales New York New Zealand Newfoundland Newfoundland and Labrador next generation biofuels next generation vehicles NHRA drag racing Nicaragua nickel Niger Nigeria nipa sap nitrate leaching nitrates nitrogen Nitrogen fertiliser nitrogen starvation nitrous oxide (N2O) Niue NO2 noodles nopal North Africa North America North Carolina North Dakota North Korea Northeast northern catalpa Northern Ireland Northern Territory Northwest Territories Norwary Norway Nova Scotia NOx (nitrogen oxides) noxious weeds nuclear Nunavut nut shells nutraceuticals nutrient credit trading nutrient management nutrients nutrition oak oat hulls oat straw oats Obligated Parties/Point of Obligation (PoO) ocean-based energy Oceania octane octane price/value octanol Office of Energy Efficiency and Renewable Energy Office of Management and Budget (OMB) Office of Science and Technology Policy Office of Science and Technology Policy (OSTP) Office of Science Technology and Policy (OSTP) Offices of Inspector Generals offtake agreements Ohio oil oil embargo oil exploration oil monopoly oil p oil price parity oil prices oil production oil refineries oil replacement oil sands oil seed oil seed crops oil speculators oil spill oil subsidies oil taxes oil/gas terminals Oils Oklahoma olefins oligomerization olive cake olive oil olive pits olive pomace olive water olives Oman Omega-3s on-farm algae production on-farm ammonia production on-farm biodiesel on-farm ethanol production on-farm natural gas production on-farm processing on-site hydrogen production one p one pound waiver onion waste online courses Ontaio Ontario OPEC (Organization of the Petroleum Exporting Countries) open fuel standard open pond opportunity zones optimized flex fuel vehicles orange peel orchard grass orchard prunings Oregon organic solar cells Organization for Economic Cooperation and Development (OECD) osage orange OSHA Overseas Private Investment Corporation overview overview/survey course owa oxygen oxygenate ozone Pakistan Palau palm palm biomass palm fatty acid distillate palm fiber palm fronds palm kernel palm kernel oil palm kernel shell palm oil Palm Oil Methyl Ester (PME) palm oil mill effluent (POME) palm oil prices palm trunk sap palm waste Paludiculture/peatland cultivation Panama pandas panic grass papaya paper Papua Indonesia Papua New Guinea paraffins Paraguay Paris Agreement parity partial waiver particulates pasture land Patent and Trademark Office (PTO) patents pathways Paulownia paulownia tree payments peach shell peaches peak oil peak oil demand peanuts/groundnuts peas pectin peela kaner pellet pellets Pennsylvania pennycress/stinkweed pentane pentanol pentose pequi perennial grains perennial grasses Performance permitting Peru pest-tolerance pesticide-tolerance pests pet food petition petroleum pharmaceuticals phase separation Philippines phosphorus photobioreactor 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(Ribonucleic acid) RNG tax credit roadmap rocket fuel Romania RON (Research Octane Number) rosin rotation crops Roundtable on Sustainable Biomaterials (RSB) royalties RP-1 RTP (rapid thermal processing) rubber rubber seeds rumen ruminants rural development Rural Energy for America Program (REAP) Rural Energy Self-Sufficiency Initiative Rural Renewable Energy Pilot Program rushes Russia Russian olive rutabaga Rwanda ry rye Rye grass rye straw s saccharification SAF pipeline SAF10 SAF30 SAF40 SAFc (Sustainable Aviation Fuel certificates) Safer and Affordable Fuel Efficient Vehicles (SAFE) safety safflower sago pond weed SAIC sal tree Salicornia salt water salt-tolerant saltbush saltcedar Samoa Sanctions Santa Monica sardine oil Saskatchewan Saudi Arabia sawdust scale up Scandinavia scholarships/fellowships Science Advisory Board (SAB) Science Based Targets initiative (SBTi) Science Policy scooters Scotland scum sea level rise seaports seashore mallow seawater seaweed cultivation 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