by Jim Lane (Biofuels Digest) A handful of industrial biotechnology companies have the strength and purpose to make it as a public company — others remain private, are acquired, or wind down. What makes companies able to succeed with public investors?
genetically enhanced microbes
Back TO HOMEEPA, FDA, and USDA Issue Joint Regulatory Plan for Biotechnology
(U.S. Food and Drug Administration) In response to President Biden’s Executive Order 14081, “Advancing Biotechnology and Biomanufacturing Innovation for a Sustainable, Safe, and Secure American Bioeconomy,” the U.S. Environmental Protection Agency (EPA), the U.S. Food and Drug Administration (FDA), and
May 08, 2024 Read Full Article
Law Library of Congress Publishes Report on Selected Issues in Biotechnology Regulation
by Lynn L. Bergeson and Carla N. Hutton (Bergeson & Campbell) The Law Library of Congress published a November 2023 report entitled Selected Issues in Biotechnology Regulation: Australia, Belgium, Brazil, Canada, China, England, European Union, Germany, India, Japan, Mexico, New Zealand, Singapore,
January 22, 2024 Read Full Article
Opinion: Climate Change and Hunger Are Here Now—a New Farm Bill Can’t Wait
by Beth Ellikidis (Biotechnology Innovation Organization/Agri-Pulse) ... One way to reduce greenhouse gas emissions and protect our climate is by getting more of the energy we use from above the ground instead of beneath it. The biotech company LanzaTech genetically engineers microbes to
October 25, 2023 Read Full Article
United Signs Agreement to Buy up to One Billion Gallons of Sustainable Aviation Fuel from Cemvita
(Cemvita/Business Wire) Cemvita designs synthetic microbes that have the potential to convert CO2 into sustainable aviation fuel (SAF) -- Cemvita Corporation announced an offtake arrangement with United Airlines for up to 1 billion gallons of sustainable aviation fuel (SAF) from Cemvita’s first full-scale SAF
September 18, 2023 Read Full Article
The Pathways to Biofuels: A Survey of Why We Should Stop Fretting
byMichael Barnard (CleanTechnica) We have enough waste biomass feedstock to fulfill all of our transportation needs, and the market and a bunch of bright people will figure out which ones are cheapest and lowest impact. ... And in this future world of
May 24, 2023 Read Full Article
Cemvita Unveils eCO2 Pilot Plant: Transforming CO2 Emissions into Renewable Feedstocks and Fertilizers
(Cemvita/Business Wire) eCO2TM platform promises to alleviate feedstock shortage and produce carbon-negative fuels and chemicals at competitive market rates -- Cemvita, the standard for biosolutions in the energy industry, today announced the opening of a pilot plant in Houston, TX. The
April 13, 2023 Read Full Article
Growing In Iowa: The Future of Food and Farming -- Pivot Bio Improves Grower Access to a Dependable Nitrogen Source
by Jim Lane (Biofuels Digest) From his time at the University of Iowa to the first startup he founded with support from the John Pappajohn Entrepreneurial Center, Karsten Temme, Ph.D., credits much of his accomplishments as Pivot Bio CEO and co-founder to the invaluable
April 11, 2023 Read Full Article
B-Harmony: Creating Happy Bacterial Colonies and Ridding the World of Its Methane Malaise, the Windfall Bio Way
by Jim Lane (Biofuels Digest) ... So, let us introduce Windfall Bio, just now emerging from many moons of stealth. News has arrived from Windfall’s Menlo Park Hq that the company has closed a $9 million seed round led by
April 10, 2023 Read Full Article
Researchers Prove that Tough, Woody Lignin Can Be Broken Down in an Anaerobic Environment
by Sonia Fernandez (University of California - Santa Barbara/Phys.Org) It's a tough job, but someone's got to do it. In this case, the "job" is the breakdown of lignin, the structural biopolymer that gives stems, bark and branches their signature
March 17, 2023 Read Full Article
UW–Madison Research Key to Decarbonization Plan
by Chris Hubbuch (Great Lakes Bioenergy Research Center) Researchers at the University of Wisconsin–Madison are working to develop plant-based fuels that are a key piece of the nation’s blueprint for decarbonizing transportation. ... That will require sustainable alternatives to gasoline,
February 07, 2023 Read Full Article
Products Made with Captured Greenhouse Gas Are Reaching Commercial Scale
By Dieter Holger (Wall Street Journal) Straws, bottles and packaging made with captured greenhouse-gas are starting to reach commercial scale, offering a way for businesses making and using everyday products to reduce emissions contributing to global warming. Locking up greenhouse gas in
November 29, 2022 Read Full Article
PNNL Team Recognized with ACS Award for Affordable Green Chemistry
by Mary Ann Showalter (Pacific Northwest National Laboratory) The American Chemical Society (ACS) has announced that development of a catalytic process and catalyst to create sustainable aviation fuel is receiving the 2023 ACS Award for Affordable Green Chemistry. The team named in the
September 30, 2022 Read Full Article
DOE Announces $178 Million to Advance Bioenergy Technology
(U.S. Department of Energy) 37 Projects Will Develop New Technologies That Engineer Plants and Microbes into Bioenergy and Improve Carbon Storage -- The U.S. Department of Energy (DOE) today announced $178 million for bioenergy research to advance sustainable technology breakthroughs that
September 15, 2022 Read Full Article
4H Club, Methane to the Rescue: The Calysta, Mango Materials, Industrial Microbes, T2C Energy Stories
by Jim Lane (Biofuels Digest) Biogas is an ancient thing, organisms have been making it for millenia – only in recent decades have we learned to capture and use it to generate on-site heat and power. ... ... This is the supply
September 13, 2022 Read Full Article
Biden Executive Order to Fund U.S. Biomanufacturing Industry
by Trevor Hunnicutt (Reuters) President Joe Biden will sign orders on Monday to push more government dollars to the U.S. biotechnology industry, aimed at reducing dependence on China for materials to generate clean energy, weave new fabrics and inoculate populations against
September 12, 2022 Read Full Article
New DOE Request for Information Released on Biomass Conversion Research, Development, and Analysis Programs DEADLINE March 11, 2022
(U.S. Department of Energy) The U.S. Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) Bioenergy Technologies Office (BETO) has released a new request for information (RFI) on several priority areas relating to activities in the Conversion Research and Development (R&D)
February 01, 2022 Read Full Article
Zara, LanzaTech’s Steel Factory Waste Emissions Fashion, Largest Cultured Steak Printed to Date, Adidas, Allbirds on Low-Carbon Cootwear and More: The Digest’s Top 8 Innovations for the Week of December 16th
by Helena Tavares Kennedy (Biofuels Digest) Zara clothing made from steel factory waste emissions thanks to LanzaTech, adidas and Allbirds scaling up their low-carbon footwear, Canadian brand launches apple leather handbags, new fruit-based glitter for your holiday festivities, and the largest
December 16, 2021 Read Full Article
Using Microbes to Make Carbon-Neutral Fuel
by Talia Ogliore (The Source) Researchers at Washington University in St. Louis have discovered a new way to train microbes to make a readily usable biofuel. A team of biologists and engineers modified a microbe called Rhodopseudomonas palustris TIE-1 (TIE-1) so that it can
November 04, 2021 Read Full Article
Pluton Biosciences Gets $6.6M in Seed Funding, Bayer AG Soil Deal and More
by Helena Tavares Kennedy (Biofuels Digest) Pluton is a large body of intrusive igneous rock according to the Merriam-Webster Dictionary, and “breaking ground” and being “ground breaking” is just what Pluton Biosciences is doing with their novel microbes. They are making
October 11, 2021 Read Full Article
Engineered Yeast Could Expand Biofuels' Reach
by Anne Trafton (Massachusetts Institute of Technology/Phys.Org) To try to expand biofuels' potential impact, a team of MIT engineers has now found a way to expand the use of a wider range of nonfood feedstocks to produce such fuels. At the
June 28, 2021 Read Full Article
Economical Cell-free Isobutanol Production: The Digest’s 2021 Multi-Slide Guide to Invizyne Technologies
by Jim Lane (Biofuels Digest) Biomass derived sugars can be used by engineered microbes to make fuels and chemicals – but Invizyne is looking at alternative methods to improve cellulosic utilization and conversion. Check out their BETO presentation highlighting their
June 01, 2021 Read Full Article
I Got 99 Problems but Product vs. Platform Ain’t One: Introducing Microbes-as-a-Service
by Moji Karimi (Cemvita Factory/Biofuels Digest) Any SynBio (synthetic biology) company is faced with three principal questions right off the bat: 1. Product or platform? A) Product: develop the microbe, build the plant, and sell the product. The end molecule is the revenue
May 13, 2021 Read Full Article
The Green Secrets of Goat Poop – Smarter Materials, Better Medicines, and Sustainable Biofuels
(Lawrence Berkeley National Laboratory/SciTechDaily) Microbes found in the goat gut microbiome could help humans convert plant material into valuable, eco-friendly commodities. Converting the tough fibers and complex sugars in plants into biofuels and other products could be humanity’s ticket to smarter materials,
March 16, 2021 Read Full Article
From Biofuels and Other Chemicals to Methane Production: Study Peers into the Mysteries of a Goat's Gut
by Sonia Fernandez (University of California - Santa Barbara/Phys.Org) ... "This has been the longest single effort in my lab," said (Michelle) O'Malley, who with her research team way back in 2015 first embarked on an ambitious project to characterize gut
February 02, 2021 Read Full Article
Engineered Pseudomonas putida Simultaneously Catabolizes Five Major Components of Corn Stover Lignocellulose: Glucose, Xylose, Arabinose, p-coumaric Acid, and Acetic Acid
by Joshua R.Elmore, Gara N.Dexter, DaviniaSalvachúa, MarykateO'Brien, Dawn M.Klingeman,KentGorday, Joshua K.Michener, Darren J.Peterson, Gregg T.Beckham, Adam M.Guss (Metabolic Engineering) Engineered P. putida to catabolize xylose and arabinose. Identified bottlenecks in xylose catabolism in P. putida and improved growth rate. Max sugar consumption rate in
September 17, 2020 Read Full Article
On a Molecular Level: The Digest’s 2020 Multi-Slide Guide to Checkerspot’s Microbes to Products
by Jim Lane (Biofuels Digest) A company that designs materials at a molecular level by optimizing microbes to biomanufacture unique structural oils discovered in nature, but not previously accessible commercially, is what Checkerspot is all about. Check out their Slide Guide from
July 15, 2020 Read Full Article
Research Brief: Engineering Natural Selection in Microbes Has Implications for Biofuel Production, Addressing Antibiotic Resistance
(University of Minnesota) ... “So many other things change around a gene at the same time, you can’t focus on how a single gene changes,” said Michael Travisano, a professor in the University of Minnesota College of Biological Sciences’ Department of Ecology, Evolution, and Behavior and
May 08, 2020 Read Full Article
Automated Microfluidic System Saves the Day for Microbes, Enzymes, Proteins: The Digest’s 2019 Multi-Slide Guide to Efficient Robotics
by Jim Lane (Biofuels Digest) Domo arigato Mr. Roboto – How would you like an automated microfluidic system to help create an ultra-high throughput workstation for the screening and optimization of microbial strains, cell lines, enzymes, proteins and peptides? Efficient Robotics has
December 11, 2019 Read Full Article
Biofuels That Could Be Made from Seawater
(University of Manchester/Phys.org) Researchers from the University of Manchester are using synthetic biology to explore a more efficient way to produce the next generation of biobased jet fuels—partly made from seawater. -- The Manchester research group, led by Professor Nigel Scrutton,
October 18, 2019 Read Full Article
Magnificent Microbes: The Digest’s 2019 Multi-Slide Guide to Targeted Microbial Development
by Jim Lane (Biofuels Digest) The industry is always on the look for microbial pathways that are capable of producing high carbon efficiency intermediates that are amenable to economic bioconversion, separation, and catalytic upgrading to hydrocarbon fuels and chemicals. At
October 01, 2019 Read Full Article
Contract Fermentation Update, Market Continues to Tighten
by Mark Warner (Warner Advisors LLC) ... Contract manufacturing options are diminishing and the facilities currently operating are looking for more favorable commercial terms. If you are planning to scale a fermentation process through contract fermentation facilities, it is going
September 11, 2019 Read Full Article
Sayings and Images from 12 Years Traveling on the Bioeconomy Road
by Jim Lane (Biofuels Digest) Today, the Digest turns 12. Since the Digest was launched in July 2007, we’ve had the privilege of telling the amazing success story of the bioeconomy— new applications, companies, and platform technologies have been pouring out of
July 29, 2019 Read Full Article
Efficiently Producing Fatty Acids and Biofuels from Glucose
(The Korea Advanced Institute of Science and Technology (KAIST)/Phys.Org) Researchers have presented a new strategy for efficiently producing fatty acids and biofuels that can transform glucose and oleaginous microorganisms into microbial diesel fuel, with one-step direct fermentative production. The newly developed strain,
June 19, 2019 Read Full Article
New Microorganism for Algae Biomass to Produce Alternative Fuels
(Bioenergy Insight) Professor Gyoo Yeol Jung and his research team utilised algae that grow three times faster than starch crops and succeeded in producing biofuel and biochemicals. ... (T)he joint research team of the Pohang University of Science and Technology (Postech) and Seoul
June 18, 2019 Read Full Article
Biomanufacturing 2.0 Cell-Free: The Digest’s 2019 Multi-Slide Guide to Invizyne Technologies
by Jim Lane (Biofuels Digest) Invizyne Technologies is making chemicals the cell-free way using synthetic biology and metabolic engineering. By inputting sugar and using engineered microbes, they can result in useful compounds and commodity chemicals, biofuels, fuel additives, fragrances, and pharmaceuticals. James
June 13, 2019 Read Full Article
Researchers Create Microorganism for Algae Biomass to Produce Biofuel and Biochemical
(AZO CleanTech) ... (T)he collaborative research team of POSTECH and Seoul National University created a new microorganism, which they christened as Vibrio sp. dhg. In their research, they effectively showed that Vibrio sp. dhg can be a capable microbial platform for the
June 13, 2019 Read Full Article
Startups Strive to Recycle Emissions for 'New Carbon Economy'
by Sebastien Malo (Reuters) Jennifer Holmgren, chief executive of carbon recycling firm LanzaTech, explained modestly how the Chicago-based startup had cut multi-million-dollar deals on four continents, including in China, aimed at helping curb climate change and air pollution. At the Jingtang Steel Mill
May 31, 2019 Read Full Article
Six MSU Researchers Receive Prestigious NSF Early Career Awards
(Michigan State University) ... Daniel Ducat, assistant professor in the Department of Biochemistry and Molecular Biology, received $1,033,970 from NSF’s Division of Systems and Synthetic Biology to investigate the fundamental interactions that underpin resilient microbial partnerships and may be key to solving
May 28, 2019 Read Full Article
Engineered Bacteria Could Be Missing Link in Energy Storage
by Krishna Ramanujan (Cornell Chronicle) One of the big issues with sustainable energy systems is how to store electricity that’s generated from wind, solar and waves. At present, no existing technology provides large-scale storage and energy retrieval for sustainable energy at
May 23, 2019 Read Full Article
Better Bugs as Drugs: The Digest’s 2019 Multi-Slide Guide to SCIBAC
by Jim Lane (Biofuels Digest) SCIBAC has developed a patented MERGE (Microbial Enhanced Recombinants Generated by Evolution) platform for strain improvement works by harnessing and directing a natural evolutionary process where different species can mate. Jeanette Mucha, CEO, Chief Science Officer and
April 29, 2019 Read Full Article
Worcester Polytechnic Institute Helps Develop a Novel Extraction Process that May Provide a More Economical Way to Make a Promising Biofuel
(Worcester Polytechnic Institute/PR Web) Isobutanol has been hailed as a possible green replacement for fossil fuels like gasoline, but producing it has proven difficult and costly. In a paper in Nature Communications, a research team that includes a WPI chemical engineer
April 19, 2019 Read Full Article
Putting CO₂ Emissions to Work: The Digest’s 2019 Multi-Slide Guide to Opus 12
by Jim Lane (Biofuels Digest) Opus 12 has developed a device that recycles CO₂ into cost-competitive chemicals and fuels. Their technology bolts onto any source of CO₂ emissions, and with only water and electricity as inputs, transforms that CO₂ into some
April 19, 2019 Read Full Article
BioAg of the Future: The Digest’s 2019 Multi-Slide Guide to Novozymes BioAg
by Jim Lane (Biofuels Digest) Novozymes is the world leader in biological solutions focusing on enzymes and microbes. Since 2000, they have brought more than 100 new molecules to market to address specific industry and customer challenges. We account for 2/3
April 16, 2019 Read Full Article
From Bioenergy to Bioproducts: The Digest’s 2019 Multi-Slide Guide to JBEI
by Jim Lane (Biofuels Digest) Joint BioEnergy Institute is a U.S. Department of Energy Bioenergy Research Center dedicated to developing advanced biofuels—liquid fuels derived from the solar energy stored in plant biomass that can replace gasoline, diesel and jet fuels. Inside
April 12, 2019 Read Full Article
Methane to Chemicals: The Digest’s 2019 Multi-Slide Guide to iMicrobes
by Jim Lane (Biofuels Digest) Industrial Microbesupgrades methane to various multi-carbon chemicals using synthetic biology. Noah Helman, CSO and Co-Founder of iMicrobes gave this illuminating overview of methane as a feedstock, the breakthrough in active MMO in E.coli that has allowed easier methane
March 21, 2019 Read Full Article
What a Microbe Would Say on Glassdoor
by Mark Warner (Warner Advisors LLC/Biofuels Digest) In my previous article on Scale-up from the Microbes Perspective, I discussed how the biotechnology commercialization process would be viewed by a microbe. This is a little lighter topic than the engineering subjects I usually write
March 19, 2019 Read Full Article
Engineered Microbe May Be Key to Producing Plastic from Plants
by Chris Barncard (University of Wisconsin-Madison) With a few genetic tweaks, a type of soil bacteria with an appetite for hydrocarbons shows promise as a biological factory for converting a renewable — but frustratingly untapped — bounty into a replacement for
March 11, 2019 Read Full Article
No Carbon Left Behind: The Digest’s 2019 Multi-Slide Guide to LanzaTech
by Jim Lane (Biofuels Digest) LanzaTechhas over 20 years experience sourcing and supplying over 5 million tons of wood fiber and organic feedstock in markets across North America. They offer biomass feedstock supply and analytics to understand and minimize supply chain
February 05, 2019 Read Full Article
E. coli Takes On Biofuels
by Jessica Velez, Angel Fernando Cisneros Caballero and Narjes Alfuraiji (Science Trends) ... In the genetic engineering world, E. coli is a valuable user-friendly host with a well-known growth metabolism and the largest set of genetic engineering tools available. Many people may
January 25, 2019 Read Full Article
New Biosensor Highlights Best Biofuel-Producing Microbes
by Max Witynski (Great Lakes Bioenergy Research Center/University of Wisconsin-Madison) A major goal of the Great Lakes Bioenergy Research Center is to harness the power of microbes to create biofuels. But often, it’s an expensive challenge for scientists to identify the most useful
January 24, 2019 Read Full Article
ExxonMobil and Renewable Energy Group Partner with Clariant to Advance Cellulosic Biofuel Research
(ExxonMobil/Renewable Energy Group/Globe Newswire) Partnership to expand on joint ExxonMobil and REG research into cellulosic biodiesel; Clariant’s sunliquid® technology to facilitate creation of compatible cellulosic sugars; Objective is to combine technologies into a single, integrated biodiesel production process ExxonMobil and Renewable Energy Group (REG)
January 23, 2019 Read Full Article
Pushing Microbes to Deliver Preferred Products
by Tom Ziemer (University of Wisconsin-Madison/Phys.Org) If environmental engineer Daniel Noguera had his way, he would orchestrate a microbiome to pump out higher-value chemical products. In that vein, Noguera, the Wisconsin Distinguished Professor of civil and environmental engineering at the University of Wisconsin-Madison, along
January 16, 2019 Read Full Article
Scale-Up From the Microbes Perspective
by Mark Warner (Warner Advisors LLC/Biofuels Digest) On a biotechnology project years ago, one of the team members responsible for biological advancement referred to themselves as the microbial organisms “shop steward”, a reference to union representation. While it was somewhat in jest,
January 09, 2019 Read Full Article
Designed Materials Innovation: The Digest’s 2018 Multi-Slide ABLC Guide to Checkerspot
by Jim Lane (Biofuels Digest) Checkerspot designs high performance materials such as microbes to express new molecular building blocks that they then apply chemistry to create materials that are built into parts and products they prototype. Charles Dimmler, Checkerspot’s CEO gave this
December 27, 2018 Read Full Article
The BioIncredibles 2: iMicrobes Is Using Methane to Produce Chemicals, and Mikey the Microbe Likes It
by Jim Lane (Biofuels Digest) ... The achievement of a major proof of concept is the news, in the case of Industrial Microbes — the ability to show that they can convert methane into multiple products (albeit at low efficiency, in
December 20, 2018 Read Full Article
A Kill Switch For Genetically Modified Algae
(Hiroshima University/Asian Scientist Magazine) By preventing bioengineered microalgae from growing outside the lab, researchers have reduced the risk of the genetically modified organisms escaping into the wild. Researchers at Hiroshima University, Japan, have developed a biocontainment strategy for genetically modified microalgae. They
December 13, 2018 Read Full Article
Zymergen, the Porsche 911 of the Materials Superhighway, Raises $400M in Monumental Series C Round
by Jim Lane (Biofuels Digest) ... In California, Zymergen has raised over $400 million in Series C funding led by returning investor SoftBank Vision Fund. The round welcomes new investors Goldman Sachs and Hanwha Asset Management, as well as returning
December 13, 2018 Read Full Article
Presentations Available from the Workshop on Opportunities and Challenges in Anaerobic Digestion Maryland and the Northeast US Experience
(University of Maryland) Workshop on Opportunities and Challenges in Anaerobic Digestion Maryland and the Northeast US Experience Topics •Anaerobic Digestion: Where We Are Today •Digester Systems in the Northeast–Successful Case Studies •Federal Biogas Policy •MD State Biogas Policy •Use of Biogas: Scrubbing, RNG, GenSets, and Use
November 02, 2018 Read Full Article
Sampling Guts of Live Moose to Understand How They Break down Biomass
(Environmental Molecular Sciences Laboratory/Phys.Org) Microbes in the gastrointestinal tract of ruminants such as moose help break down recalcitrant plant biomass into carbon nutrients, but how do they do this over the course of seasons when the moose diet changes, and what
October 26, 2018 Read Full Article
Lego’s Biobased Bricks; Vertoro’s Green Crude Oil; Nitogen-Fixing Microbes for Corn; Diapers from Food Waste; 3D Imaging; Apeel’s $70M: The Digest’s Top 10 Innovations for the Week of August 15th
by Jim Lane (Biofuels Digest) The pace of invention and change is just too strong, we’ve realized, to highlight annual or even quarterly or monthly rankings and summaries of significant product and service advances. For now, we’re going to be tracking
August 16, 2018 Read Full Article
Complex Networks Identify Genes for Biofuel Crops
(U.S. Department of Energy/Phys.Org) To improve biofuel production, scientists must understand the fundamental interactions that lead to the expression of key traits in plants and microbes. To understand these interactions, scientists are using different layers of information (about the relationships
August 15, 2018 Read Full Article
Brief Thoughts on the 2018 Bio World Congress on Industrial Biotechnology (July 16-19, 2018, Philadelphia, PA)
by Craig Laufer* (Advanced Biofuels USA) After hearing from many speakers at the BIO World Congress on Industrial Biotechnology, one recurring theme from the sessions I attended was the application of digital biology, synthetic biology in silico modeling, machine learning
August 07, 2018 Read Full Article
This Start-Up Turns Pollution from Factories into Fuel That Powers Cars — and One Day Planes
by Catherine Clifford (CNBC) A bacteria found in the gut of a rabbit can now help cars run in a more eco-friendly way. The bacteria, identified by biotech start-up LanzaTech, helps turn factory carbon emissions, a.k.a. pollution, into ethanol .... ... "While there are many sustainable
July 30, 2018 Read Full Article
Synthetic Methylotrophy: The Digest’s 2018 Multi-Slide Guide to Engineering Platform Organisms for Methane & Methanol Conversion to Fuels & Chemicals
by Jim Lane (Biofuels Digest) Harnessing Methane & Methanol as Feedstocks, that’s the subject of this overview of the uses of methanol when used by engineered platform organisms for fuel and chemical production. The background is the abundant CH4supply of recoverable
July 03, 2018 Read Full Article
The Yosemite Sam of the Microbial World, Hot Rodded Lichen, BYO Nitrogen, The Microbial Marx Brother, Sexy Hexy and More: The DOE Delves into New Orgamsism for Fuels & Chems
by Jim Lane (Biofuels Digest) The meanest, nastiest, ornierest, heat-seeking organism ever found that munches biomass and other microbes that got a booster via the DOE’s $40M grants for advanced microbes R&D. And aromatics without the mess, a sky-vacumming organism and
June 28, 2018 Read Full Article
Department of Energy Announces $40 Million for Bio-Based Research
(U.S. Department of Energy) 31 Projects Will Help Advance Fundamental Science for Bioenergy -- Today, the U.S. Department of Energy (DOE) announced $40 million in funding for 31 projects to advance research in the development of microbes as practical platforms for the
June 20, 2018 Read Full Article
New Machine Learning Approach Could Accelerate Bioengineering
(Lawrence Berkeley National Laboratory/Biomass Magazine) Scientists from the Department of Energy’s Lawrence Berkeley National Laboratory have developed a way to use machine learning to dramatically accelerate the design of microbes that produce biofuel. Their computer algorithm starts with abundant data about the
June 07, 2018 Read Full Article
The Scientist Still Fighting for the Clean Fuel the World Forgot
by James Temple (MIT Technology Review) In the closing weeks of 2008, the US Department of Energy invited politicians and press to a dedication ceremony for the Joint BioEnergy Institute in Emeryville, California. The state-of-the-art lab, backed by $125 million in
May 16, 2018 Read Full Article
The Digest’s Top 10 Innovations, 3.28.18 Release
by Jim Lane (Biofuels Digest) According to BIO, the global economic value today of the biobased economy – including industrial biotechnology, renewable chemicals and polymers, biofuels, enzymes and biobased materials – is $355.28 billion. And looking at the new USDA Indicators report
March 30, 2018 Read Full Article
Biorefineries: Our Synthetic Biology Future
by Bob Kodrzycki (Encompass Biotech LLC/Lee Enterprises Consulting/Biofuels Digest) ... Opportunity, such as the availability of a new feedstock or the possibility of combining technologies can lead to very interesting outcomes. ... Technology alone is usually not enough to develop a market. But combined
February 09, 2018 Read Full Article
Boosting Ethanol’s Value via CO2 Use: The Digest’s 2017 Multi-Slide Guide to White Dog Labs
by Jim Lane (Biofuels Digest) US-based White Dog Labs have developed a new process that eliminates the production of CO2, a potent greenhouse gas, during fermentation and instead shifts the carbon to added ethanol production, boosting fermentation yields by around 50
December 27, 2017 Read Full Article
New Pathways, Better Biofuels
by Erika Ebsworth-Goold (Washington University in St. Louis/The Source) An engineering team at Washington University in St. Louis is using e. coli to manufacture biofuel. New research from the lab further refines the process. ... Scientists have previously engineered metabolic pathways of microbes,
November 28, 2017 Read Full Article
ExxonMobil and REG Expand Cellulosic Biodiesel Research
by Joseph Bebon (NGT News) ExxonMobil and Renewable Energy Group (REG) announced that by utilizing REG’s patented fermentation technology, the companies’ joint research program has demonstrated the ability to convert sugars from a variety of non-edible biomass sources into biodiesel. ... During their initial research, the
November 02, 2017 Read Full Article
Clariant to Build Flagship Cellulosic Ethanol Plant in Romania: 8-Figure Sales Potential Envisioned
by Jim Lane (Biofuels Digest) In Germany, Clariant’s board has approved investment in a new full-scale commercial plant for the production of cellulosic ethanol from agricultural residues using its sunliquid technology. The new plant, with an annual production capacity of 50.000
November 01, 2017 Read Full Article
Making Renewables Mainstream: The Digest’s 2017 Multi-Slide Guide to Amyris
by Jim Lane (Biofuels Digest) We reported on Amyris’ progress recently in “The New Colossus aims to unlock its Golden Door” and in Two Up: Amyris, Queensland gamble on farnesene for SE Asia. Meanwhile, Amyris President of R&D Joel Cherry presented these illuminating
October 27, 2017 Read Full Article
Methane for Supper: The Digest’s 2017 Multi-Slide Guide to Industrial Microbes
by Jim Lane (Biofuels Digest) iMicrobes designs and builds microorganisms, including industrial strains of bacteria and yeast to produce chemicals from natural gas and carbon dioxide. Their green, bio-based methods are “more cost effective than sugar or oil, helping to make
October 20, 2017 Read Full Article
Advanced Fermentation Agitation with Methanotrophs and Other Organisms
by Gregory T. Benz (Lee Enterprises Consulting/Biofuels Digest) Fermentation processes, both aerobic and anaerobic, have been successful on an industrial scale for quite a long time, producing a wide variety of products. In most of these processes, if any gas
August 09, 2017 Read Full Article
The Digest’s 2017 Multi-Slide Guide to Verdezyne
by Jim Lane (Biofuels Digest) Verdezyne is a privately held industrial biotechnology company that is developing and commercializing novel genetically engineered microorganisms for use as “factories” to manufacture renewable chemicals. Verdezyne’s unique microorganisms permit greener, cleaner and more cost effective
July 04, 2017 Read Full Article
N-butanol and Beyond: The Digest’s 2017 Multi-Slide Guide to Green Biologics
by Jim Lane (Biofuels Digest) Green Biologics is focused on the production of renewable n-butanol and other C4 chemicals from various renewable feedstocks, including sugar (cane, molasses, beets), starch (corn) and cellulosic biomass (corn residues, sugar cane bagasse, forest materials
June 28, 2017 Read Full Article
Little Big Ally: The Digest’s 2017 Multi-Slide Guide to Ginkgo BioWorks
by Jim Lane (Biofuels Digest) Ginkgo Bioworks designs custom microbes for customers across multiple markets. We build our foundries to scale the process of organism engineering using software and hardware automation. Organism engineers at Ginkgo learn from nature to develop
May 17, 2017 Read Full Article
A New Hydrocarbon Brew: The Digest’s 2017 Multi-Slide Guide to Technical Market Analysis for Biochemical Conversion
by Jim Lane (Biofuels Digest) As the project team behind this presentation explains, there’s trouble right here in River City when it comes to accessing good market and technical data on making hydrocarbons from a biochemical process. Process and economic data
February 16, 2017 Read Full Article
A Critical Look at Cellulosic Ethanol and Other Advanced Biofuels
by Alexander A. Koukoulas0 (ANL Consultants LLC/Biofuels Digest) ... The pursuit of 2nd Gen fuels has been motivated by several factors including: their inherently low-cost, at least from a theoretical standpoint; their potential for drastically reducing carbon emissions relative to 1st Gen
December 13, 2016 Read Full Article
EPA Biotech Review Staff Prepares To Handle Engineered Microorganism TSCA Submissions
(Biobased and Renewable Products Advocacy Group) On November 9, 2016, Inside EPA published “New TSCA Requirements Raise Challenges To EPA Biotech Review Staff” (subscription required), outlining what EPA has done to adapt to revised Toxic Substances Control Act (TSCA) requirements
November 16, 2016 Read Full Article
Bacteria Turn Trees into Pollution-Eating Machines
by Anthony King (Horizon Magazine) Hacking trees by adding bacteria to their roots could help scrub contaminated soil clean of chemicals and metals from industrial spillages and fallouts, a process known as gentle remediation. Once the approach is refined, it could
November 14, 2016 Read Full Article
Strategic Intent: The Digest’s 2016 Multi-Slide Guide to Evonik in the Advanced Bioeconomy
by Jim Lane (Biofuels Digest) This season, The Digest is hosting the Strategic Intent webinar series, looking at the plans, progress and future milestones of strategic stakeholders in the Advanced Bioeconomy. In this slide deck, we looked at Evonik and its direct investments, partnerships
September 08, 2016 Read Full Article
US Researchers Get Go Ahead to Genetically Engineer Bacteria to Boost Bioethanol Production
(Biofuels International) lllinois Institute of Technology researchers have received a patent for a method to genetically engineer bacteria and yeast to increase bioethanol production, especially from cellulosic material in biomass like twigs, branches, plant stalks and husks, and woodchips. According to
August 04, 2016 Read Full Article
Biological Wizardry Ferments Carbon Monoxide into Biofuel
(Cornell University/EurekAlert!) Cornell University biological engineers have deciphered the cellular strategy to make the biofuel ethanol, using an anaerobic microbe feeding on carbon monoxide - a common industrial waste gas. "Instead of having the waste go to waste, you make it
July 27, 2016 Read Full Article
Heat-Loving Microbe Engineered to Produce Bioalcohols for Fuel
(U.S. Department of Energy) Study reports first significant alcohol production by an archaeon. -- The U.S. bioethanol industry depends largely on turning a certain sugar into the simple two-carbon alcohol, the biofuel ethanol. Interest has increased around microorganisms that produce
July 05, 2016 Read Full Article
Technology, Biology, Automation, Computation: The Digest’s 2015 8-Slide Guide to Zymergen
by Jim Lane (Biofuels Digest) What’s Zymergen? As they put it, “We believe in harnessing the power of biology to make transformative products that are good for business, people and the environment. By applying the latest in automation, data architecture
December 04, 2015 Read Full Article
First Commercial! Construction Underway in Minnesota for Green Biologics
by Jim Lane (Biofuels Digest) ... In Minnesota, construction is now underway at the Green Biologics bio-based n-butanol and acetone manufacturing facility in Little Falls, MN. The existing manufacturing site, formerly known as The Central MN Ethanol Cooperative (CMEC), was
December 04, 2015 Read Full Article
EPA Holds Workshop For Input On Risk Assessment Of Genetically Engineered Algae
(The Biobased and Renewable Products Advocacy Group (BRAG®)) On September 30, 2015, the U.S. Environmental Protection Agency (EPA) held a workshop on genetically engineered (GE) algae to give stakeholders an opportunity to hear about EPA's plans for improving its risk
October 02, 2015 Read Full Article
BESC Creates Microbe that Bolsters Isobutanol Production
(Oak Ridge National Laboratory) Another barrier to commercially viable biofuels from sources other than corn has fallen with the engineering of a microbe that improves isobutanol yields by a factor of 10. The finding of the Department of Energy’s BioEnergy Science
August 17, 2015 Read Full Article
The Three Microb-eteers: Methanogens, Methanotrophs, Acetogens and Knallgas Bacteria
by Jim Lane (Biofuels Digest) Which microbes achieve a better, faster, cheaper transformation of the world around us? ... Down there in the mud, too small to be seen with the naked eye, are some of your new best friends.
July 31, 2015 Read Full Article
Oakbio Announces New Green Biofuel Production Platform
(Oakbio/Digital Journal) his ecoli based microbe platform expands the sources of waste materials Oakbio can convert to green, renewable fuels and other chemicals to include agricultural and municipal waste products. Oakbio announced today (May 14, 2015) the development of a novel
May 15, 2015 Read Full Article
“Faces” Debuts: New Original Series on the Advanced Bioeconomy
by Jim Lane (Biofuels Digest) The Digest’s first original series, Faces, debuts episode #1 for online viewing and download. More new episodes and new programs to come. ... the one-to-one interview program Faces. It’s here. Episode #1 features Industrial Microbes Chief Scientific
February 06, 2015 Read Full Article
X-Crobes: Kuraray Invests in Amyris, What’s Next for Synth-Bio and Performance Molecules?
by Jim Lane (Biofuels Digest) ... In California, Amyris and Kuraray announced the expansion and extension of their ongoing collaboration in high performance polymers using Biofene, Amyris’s brand of renewable farnesene. Amyris and Kuraray launched the collaboration in 2011 with an initial
April 02, 2014 Read Full Article
Colorado State University Researchers Explore Creating Biofuels through Photosynthesis
(Colorado State University) An interdisciplinary team of Colorado State University researchers has received a $2 million National Science Foundation grant to research new routes to the sustainable production of biofuels using photosynthetic bacteria. “The purpose of this basic research is to
July 23, 2013 Read Full Article
International Regulation of Microorganisms for Biofuel or Chemical Production: Europe, Asia and Australia
by David Glass (DGlassAssociates.com) In two blog entries in 2010, I described the possible regulatory regimes that might affect the use of genetically modified microorganisms or plants in the production of biofuels or bio-based chemicals, focusing on Canada and Europe. In a post last
March 26, 2013 Read Full Article
International Regulation of Microorganisms for Biofuel or Chemical Production: North and South America and Africa
by David Glass (DGlassAssociates.com) ... The use of genetically modified microorganisms (GMOs) in manufacturing will likely face a fairly straightforward regulatory process in most countries, because such “contained” uses will generally pose far fewer hypothetical concerns about environmental or public
March 19, 2013 Read Full Article
Engineering Microbes for Sustainable Manufacturing and Better Biofuels
by Ysabel Yates (Renewable Energy World) ...Using microbes to create useful products is nothing new. Humans have been doing it for centuries to bake bread or brew alcohol, for example. More recent techniques have employed microbes in green technology,
October 26, 2012 Read Full Article
Burning Man, Burning Microbe: Biofuels beyond Biomass
by Jim Lane (Biofuels Digest) ...Are they biofuels? We think so – even if they are post-biomass. They do what organisms have done for eons to make biomass in the first place: convert lifeless CO2, sunlight and water and nutrients
October 15, 2012 Read Full Article
BioTork Announces Collaboration with BASF
(BioTork) Harnessing the Power of Adaptive Evolution to Further Improve the Efficiency of Metabolic Engineering BioTork announces collaboration with BASF to optimize certain microbial strains for the industrial production of bio-based polymers and green chemicals. After six months of collaboration, BASF and
June 14, 2012 Read Full Article
The New Biofactories
by Robert Carlson (What Matters) ...Amyris Biotechnologies has modified yeast to transform sugar into useful compounds, including malaria drugs and biofuels that can substitute for today’s jet fuel, diesel, and gasoline. The company will begin production of these fuels next
January 20, 2012 Read Full Article
Biofuels Face a Reality Check
by Lauren Sommer (KQED) ...The idea behind biofuels is pretty simple. Plants take sunlight and use that energy to make sugars. The biofuels industry wants to transform those sugars into fuel. That requires some molecular rearranging, so they’re looking to
December 28, 2011 Read Full Article
E. Coli Bacteria Engineered to Eat Switchgrass and Make Transportation Fuels
by Lynn Yarris (Lawrence Berkeley National Laboratory) Joint BioEnergy Institute (JBEI) Researchers Reach Milestone on the Road to Biofuels A milestone has been reached on the road to developing advanced biofuels that can replace gasoline, diesel and jet fuels with a
December 05, 2011 Read Full Article
Novel Gene Increases Yeast's Appetite for Plant Sugars
(Great Lakes Bioenergy Research Center) For thousands of years, bakers and brewers have relied on yeast to convert sugar into alcohol and carbon dioxide. Yet, University of Wisconsin-Madison researchers eager to harness this talent for brewing biofuels have found when
August 01, 2011 Read Full Article
Computer Software Helps Engineer Organisms
by John Roach (MSNBC) Could lead to microbes that produce drugs and biofuels A computer software program is outfitting biotechnology companies with the ability to determine the genetic plans they need to engineer microorganisms for the production of products such as
July 22, 2011 Read Full Article
Consolidated Bioprocessing: A Revolution in Biofuels Development
by Jeremy Fordham (Green-Trust.org) ...Microorganisms are incredibly abundant and diverse, especially in their metabolic functionality. Consolidated bioprocessing takes advantage of this versatility. ...Cellulose is a crystalline molecule that is critical to a plant cell’s structure, so it is hard for microbes
June 03, 2011 Read Full Article
Seventh U.S. Patent Issued to Dyadic International
(Dyadic) Dyadic International, Inc., a global biotechnology company focused on the discovery, development, manufacture and sale of enzyme and protein products and solutions for the bioenergy, industrial enzyme and biopharmaceutical industries, announced today that it has been issued U.S. Patent
February 21, 2011 Read Full Article
Bovine Bellies Yield Clues for New Biofuels
by Maggie Fox (Reuters) Researchers looking for better ways to make biofuels turned to experts at breaking down grass -- cattle -- and found more than a dozen new compounds in their guts that might help make new, cheap sources
February 06, 2011 Read Full Article
Seaweed as Biofuel? Metabolic Engineering Makes It a Viable Option
(PhysOrg.com) Is red seaweed a viable future biofuel? Now that a University of Illinois metabolic engineer has developed a strain of yeast that can make short work of fermenting galactose, the answer is an unequivocal yes. ...(M)arine biomass can be easily
December 17, 2010 Read Full Article
Hydrocarbon Fuels: Renewable Petroleum Products and Technologies
by Stephen del Cardayre (Vice President of Research and Development, LS9) LS9 has focused efforts on the development of a renewable biodiesel that will eventually be cost-competitive with petroleum without subsidies. Del Cardayre details the microbial techniques LS9 employs to turn
August 04, 2010 Read Full Article
Exploring Algae as Fuel
by Andrew Pollack (New York Times) ...“We’ve probably engineered over 4,000 strains,” said Mike Mendez, a co-founder and vice president for technology at Sapphire Energy, the owner of the laboratory. “My whole goal here at Sapphire is to domesticate algae,
July 27, 2010 Read Full Article
Accelerating Production of Advanced Biofuels with Industrial Biotech Breakthroughs
From the open plenary session of the Biomass 2008 Conference. Download PDF.
April 17, 2008 Read Full Article
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