A New Tailor-Made Approach to Biofuels
(Phys.Org/CORDIS) … Some microbes have natural structures called cellulosomes that contain cellulases, enzymes that break down cellulose efficiently into sugars. The EU-funded CELLULOSOMEPLUS project developed designer cellulosomes (DCs) to achieve high yields of fermentable sugars from the organic fraction of municipal solid waste (OFMSW) to create advanced biofuels at a low process cost.
The consortium produced the basic components of natural cellulosomes as well as other lignocellulosic enzymes and, after their assembly into DCs, characterised the hydrolysis of the OFMSW substrate. They also studied the cellulosome’s physicochemical, atomic and supramolecular structure, and the interactions of its various components. “Cellulosome architecture consists of a non-catalytic ‘scaffoldin’ subunit that carries ‘cohesins’ that are complementary recognition modules of another type of domain termed ‘dockerins’, which are carried by the enzymes and allow their integration into the complex,” explains project coordinator Dr Mariano Carrión-Vázquez.
Tailoring DCs for the several biomass lignocellulosic residues should help improve process efficiency, thus lowering production costs. “This new technology will also help to reduce Europe’s reliance on oil, strengthen SMEs within the EU, stimulate job creation and reduce the environmental impacts of the advanced biofuel sector.” READ MORE
A ‘tailor-made approach’ for biochemical and biofuel production (Biofuels International)