Increased Enzyme Binding to Substrate Is Not Necessary for More Efficient Cellulose Hydrolysis
by Dahai Gao, Shishir P. S. Chundawat, Anurag Sethi, Venkatesh Balana, S. Gnanakaran, and Bruce E. Dale (Proceedings of the National Academy of Sciences) Substrate binding is typically one of the rate-limiting steps preceding enzyme catalytic action during homogeneous reactions. However,