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Articles tagged with: synthetic biology

N-butanol and Beyond: The Digest’s 2017 Multi-Slide Guide to Green Biologics
June 28, 2017 – 10:36 am | No Comment

by Jim Lane (Biofuels Digest)  Green Biologics is focused on the production of renewable n-butanol and other C4 chemicals from various renewable feedstocks, including sugar (cane, molasses, beets), starch (corn) and cellulosic biomass (corn residues, …

Protein, Pathway Design: The Digest’s 2017 Multi-Slide Guide to Arzeda
May 23, 2017 – 11:24 am | No Comment

by Jim Lane (Biofuels Digest)  Arzeda’s proprietary technology combines targeted computational enzyme design and protein optimization with state-of-the-art metabolic bioengineering to create entirely novel designer cell factories capable of industry-scale chemical production.
CEO Alex Zanghellini gave this illuminating overview of Arzeda’s breakthrough …

New Capabilities for Genome-Wide Engineering of Yeast
May 17, 2017 – 4:32 pm | No Comment

by Claudia Lutz (Chemical and Biomolecular Engineering at Illinois)  New approach combines synthetic biology, genome editing tools, and automation to quickly and effectively produce novel yeast strains
One of humankind’s oldest industrial partners is yeast, a familiar …

Little Big Ally: The Digest’s 2017 Multi-Slide Guide to Ginkgo BioWorks
May 17, 2017 – 3:46 pm | No Comment

by Jim Lane (Biofuels Digest)  Ginkgo Bioworks designs custom microbes for customers across multiple markets. We build our foundries to scale the process of organism engineering using software and hardware automation. Organism engineers at Ginkgo …

1 Septillion Reasons Dad’s CRISPR-Cas9 May Already Be Toast
May 17, 2017 – 2:46 pm | No Comment

by Jim Lane (Biofuels Digest)  … CRISPR-Cas9 is a technique for making a cut at a desired point in a cell’s genome. You can pick the spot and do an edit. Amazing stuff. You can …

CHASSY – New EU Yeast Biotech Project
May 3, 2017 – 2:30 pm | No Comment

(CHASSY)  … Yeast is already the powerhouse behind many food flavourings, the anti-aging compound Resveratrol, the malaria drug Artemisinin, the grapefruit extract Nootkatone, insulin, bioethanol, bioplastics, and there is potential for many more industrial applications.
To better …

Textbook: Biofuels and Bioenergy
April 3, 2017 – 1:24 pm | No Comment

edited by John Love and John A.  Bryant (Wiley-Blackwell)  With increased public and scientific attention driven by factors such as oil price spikes, the need for increased energy security, and concerns over greenhouse gas emissions …

Gigabase Is the New Megabase: The Digest’s 2017 Multi-Slide Guide to Gen9
January 23, 2017 – 12:35 pm | No Comment

by Jim Lane (Biofuels Digest)  The company manufactures custom, high-quality, synthetic DNA used by scientists to construct genes, pathways, genomes and organisms that will enable the next generation of breakthroughs in biology. Word came through …

SynBioBeta — April 4-6, 2017 — London, UK
December 19, 2016 – 3:29 pm | No Comment
SynBioBeta   —   April 4-6, 2017   —   London, UK

For the 5th year in a row, SynBioBeta London 2017 will bring together thought leaders and entrepreneurs from multiple facets of the synthetic biology industry. Our focus is to unite attendees through thought-provoking talks, panels …

Second Chance Carbon: The Digest’s 2016 Multi-Slide Guide to LanzaTech
December 13, 2016 – 3:14 pm | No Comment

by Jim Lane (Biofuels Digest)  LanzaTech has developed a fully sustainable integrative gas to fuels and chemicals platform that has no impact on food, water security or high biodiversity land use.
LanzaTech’s gas fermentation platform disrupts …

The Emerging Synthetic Biology Ecosystem: The Digest’s 2016 Multi-Slide Guide to Gingko BioWorks
December 8, 2016 – 11:30 am | No Comment

by Jim Lane (Biofuels Digest)  Recently, Ginkgo BioWorks announced the launch of their next generation foundry, Bioworks2. With 125,000 square feet and an 6X expected increase in capacity compared to BioWorks 1, Bioworks2 represents a step change …

Gigabase Is the New Megabase: The Digest’s 2016 Multi-Slide Guide to Gen9
November 30, 2016 – 10:24 am | No Comment

by Jim Lane (Biofuels Digest)  The company manufactures custom, high-quality, synthetic DNA used by scientists to construct genes, pathways, genomes and organisms that will enable the next generation of breakthroughs in biology.
Founded by pioneering scientists …

Reinventing Enzymes, Molecules by Design: The Digest’s 2016 Multi-Slide Guide to Arzeda
November 14, 2016 – 11:57 am | No Comment

by Jim Lane (Biofuels Digest)  Arzeda’s proprietary technology combines targeted computational enzyme design and protein optimization with state-of-the-art metabolic bioengineering to create entirely novel designer cell factories capable of industry-scale chemical production.
CEO Alex Zanghellini gave this overview of Arzeda’s breakthrough technology …

The Digest’s 2016 Multi-Slide Guide to Innovation in Agtech, Foodtech, and Renewable Chemicals
November 8, 2016 – 10:11 am | No Comment

by Jim Lane (Biofuels Digest)  What are the true drivers of Innovation in Agtech, Foodtech, and Renewable Chemicals? AT ABLC Next in San Francisco, the opening plenary session looking at this topic featured Roger Wyse, …

Strategic Intent: The Digest’s 2016 Multi-Slide Guide to BASF, Audi
October 12, 2016 – 11:24 am | No Comment

by Jim Lane (Biofuels Digest)  This season, The Digest is hosting the Strategic Intent webinar series, looking at the plans, progress and future milestones of strategic stakeholders in the Advanced Bioeconomy.  In this slide deck, we looked …

Biorenewables Megatrends: The Digest’s 2016 Multi-Slide Guide to the Advanced Bioeconomy’s Progress
August 26, 2016 – 9:31 am | No Comment

by Jim Lane (Biofuels Digest)  This week, we conducted a webinar on Biorenewables Megatrends with NEXANT principal Ron Cascone, who gave these incisive slides on the state of commercialization in fuels, chemicals, biomaterials and nutrition. READ …

Sustainable and Low-Cost: The Digest’s 2016 Multi-Slide Guide to Competing with Sub-$50 oil
August 2, 2016 – 1:39 pm | No Comment

by Jim Lane (Biofuels Digest)  As Irshad Ahmed observed recently in The Digest, “until such time that we internalize the true life-cycle costs of extracting and using fossil fuels, and distinguishing fossil-BTUs from bio-BUTs, we will …

Big Data, Robotics and Synth Bio: Driving “The New Agriculture”
June 22, 2016 – 7:10 pm | No Comment

by Jim Lane (Biofuels Digest)  … If you haven’t been to an LP meeting before, they are generally intimate gatherings of venture capitalists, their underlying investors (the Limited Partners), portfolio company CEOs, and some thought leaders …

Of Sausage-Making, DC and Bioenergy Budgets
June 2, 2016 – 9:47 am | No Comment

by Jim Lane (Biofuels Digest)  The signals coming out of Washington DC are so confusing, you might be wondering if there’s going to be a budget for the US Department of Energy for the fiscal …

The SynBio Foundry: The Digest’s 2016 8-Slide Guide
May 27, 2016 – 2:43 pm | No Comment

by Jim Lane (Biofuels Digest)  Lawrence Berkeley National Lab, Ames National Lab, Argonne National Lab, Idaho National Lab, Los Alamos National Lab, the National Renewable Energy Lab, Oak Ridge National Lab, Pacific Northwest National Lab, …

Why Does Biology Take so Long to Make Commercial Products? A Job for BOB
May 26, 2016 – 11:19 am | No Comment

by Jim Lane (Biofuels Digest)  … (W)hy is so biology so challenging?  —  “It’s partly how we have done it. We sort through the research, then we design, and then we spend a lot of …

Renewable Specialty Chemicals: The Digest’s 2016 Multi-Slide Guide to Green Biologics
May 19, 2016 – 11:30 am | No Comment

by Jim Lane (Biofuels Digest)  Green Biologics is focused on the production of renewable n-butanol and other C4 chemicals from various renewable feedstocks, including sugar (cane, molasses, beets), starch (corn) and cellulosic biomass (corn residues, …

Harnessing Biotechnology to Accelerate Advanced Biofuels Production
April 12, 2016 – 4:42 pm | No Comment

by Jonathan Male (US Department of Energy) … From expanding the potential of diverse microbial systems to enhancing the biocatalytic capabilities of enzymes, the application of biotechnology is accelerating the development of the advanced biofuel industry.
The …

Major Advance in ‘Synthetic Biochemistry’ Holds Promise for Industrial Products and Biofuels
April 12, 2016 – 4:36 pm | No Comment

by Stuart Wolpert (University of California – Los Angeles)  UCLA biochemists have devised a way to convert sugar into a variety of useful chemical compounds without using cells  —  UCLA biochemists have devised a clever way …

Drop in, Trip Out, Turn On: The Digest’s 2016 Multi-Slide Guide to Drop-In Fuels
March 31, 2016 – 9:23 am | No Comment

by Jim Lane (Biofuels Digest)  Yesterday, we held a well-attended webinar on “Drop-In Fuels” Here below is the first slide deck presented on the day. We’ll have the remainder of slides tomorrow.
The recorded version can …

Biobased Plastics and Resins, What’s New, and Who’s Top Cat?: The Digest’s 2016 Visual Guide
March 30, 2016 – 2:13 pm | No Comment

by Jim Lane (Biofuels Digest)  Yesterday, we held a well-attended webinar on “Biobased Plastics and resins?” Here below are the slides presented on the day.  The recorded version can be accessed here.  READ MORE

Designer Enzymes and Strains: The Digest’s 2016 8-Slide Guide to Arzeda
January 22, 2016 – 11:25 am | No Comment

by Jim Lane (Biofuels Digest)  100,000+ naturally occurring molecules are known but the biosynthesis is unknown — and cannot be made economically at any scale, today. Meanwhile, millions of synthetic non-natural molecules that could be …

Plug-and Play Synthbio: Arzeda, INVISTA, Others Finding New Pathways to Affordable, Everyday Materials
January 18, 2016 – 12:55 pm | No Comment

by Jim Lane (Biofuels Digest)  A new generation of advanced technologies, based primarily in the United States but active in Europe and around the world, is changing our way of thinking about what a factory …

E Pluribus, Unum: LanzaTech, Global Bioenergies Demonstrate The Biotechnology App Store
January 11, 2016 – 12:57 pm | No Comment

by Jim Lane (Biofuels Digest)  As Global Bioenergies, LanzaTech tighten isobutene partnership, the era of “swap-in, swap out” biorefining microbes comes clear, closer  —  In France, Global Bioenergies and LanzaTech signed a new collaboration agreement …

Innovation to Tackle Climate Change and Feed a Growing Population: Commercializing Synthetic Biology
December 2, 2015 – 3:44 pm | No Comment

by Vonnie Estes (Biofuels Digest)  …  But as the land, water, and fossil fuel resources those systems rely on become scarcer, biology is offering new ways to engineer solutions.
Synthetic biology redesigns existing organisms for specific …

Oils that Aint Oils: The Digest’s 2015 8-Slide Guide to Novvi
November 17, 2015 – 10:48 am | No Comment

by Jim Lane (Biofuels Digest) Novvi LLC is a joint venture of Amyris, Inc. and Cosan S.A. Industria e Comercio created to develop, produce, market, and distribute high-performance oils and lubricants from renewable sources. Novvi draws …

Seeking Better Biofuels
October 26, 2015 – 2:47 pm | No Comment

by Melody M. Bomgardner (Chemical & Engineering News)  Researchers at the Joint BioEnergy Institute transform biomass into energy-rich fuel molecules  —   ..  JBEI researchers are zeroing in on concepts that others have decided are too …

Synthetic Biology Comes in Peace
August 28, 2015 – 8:17 pm | No Comment

by Kevin Mayer  (Genetic Engineering and Biotechnology News)  Scientists Wonder if the Public Is Prepared for Designer Genomes  — Given its current trajectory and rate of approach, synthetic biology is hurtling toward a close encounter with …

Three Recent Developments in Synthetic Biology You Need to Know
May 14, 2015 – 5:48 pm | No Comment

By Dominic Basulto (The Washington Post)  Using synthetic biology techniques, researchers have created everything from new flavors and fragrances to new types of biofuels and materials. While the innovation potential of combining biology and engineering …

Thrive, Survive, Jive or Take Five: Who Is Weathering the $50 Oil Storm in Biofuels, and How?
May 14, 2015 – 10:57 am | No Comment

by Jim Lane (Biofuels Digest)   … Survive  —  First-Gen ethanol producers. So-so. Corn prices have fallen, and though margins have been compressed and gone negative in some cases, balance sheets remain strong and the margin …

The Commercialization of Renewable Fuels, Chemicals and Biobased Product: 4 New Views, in Depth
May 13, 2015 – 12:59 pm | No Comment

by Jim Lane (Biofuels Digest)  New targets, new markets, new tech, new methods, new outcomes.LanzaTech, Genomatica, Amyris and Brazil’s CTBE share in-depth presentations from the 37th Symposium on Biotechnology for Fuels and Chemicals. 100 of …

Scientists at the J. Craig Venter Institute Publish Paper Outlining Efficient Synthetic Biology Methods to Genetically Engineer Microalgae
April 24, 2015 – 4:56 pm | No Comment

(J. Craig Venter Institute)  Results have important implications in developing algae-based products such as biofuels and chemicals  —  Scientists from the J. Craig Venter Institute (JCVI), a not-for-profit genomic research organization, published a paper today …

US Poised for Biobased Chemicals Breakout, Says National Research Council
April 6, 2015 – 2:16 pm | No Comment

by Jim Lane (Biofuels Digest)  Though challenges remain, particularly in affordable feedstock, the US National Research Council says “Despite impressive recent and projected growth, the manufacturing of chemicals using biological synthesis and engineering could expand …

Harvard Researchers Report Bacteria Breakthrough in Mass-Chemical Production
December 30, 2014 – 5:41 pm | No Comment

by Jessica Bartlett (Boston Business Journal)  A Harvard geneticist may have unlocked the code to large-scale chemical and biofuel production, saying that researchers used the theory of evolution to trick bacteria into mass-making useful chemicals.
Reported …

Connecting the Microcosmos and the Macro World
November 5, 2014 – 3:31 pm | No Comment

by Glen Martin (O’Reilly Radar)  Christina Agapakis explores the microbiological matrix that binds everything from pecorino to people.

Agapakis is first and foremost a synthetic biologist and a microbiologist, but she’s not particularly happy with the …

Transforming Toxic Waste into Green Energy
November 3, 2014 – 5:44 pm | No Comment

by Christian Durand (Concordia University)  Emerging graduate research at Concordia seeks to turn pulp mills into dynamic biorefineries
How can a struggling industry like pulp and paper in Canada be revived? According to Damien Biot-Pelletier, a Concordia …

An Ecological Risk Research Agenda for Synthetic Biology
June 9, 2014 – 5:44 pm | No Comment

(Synthetic Biology Project)  Environmental scientists and synthetic biologists have for the first time developed a set of key research areas to study the potential ecological impacts of synthetic biology, a field that could push beyond …

Companies Quietly Apply Biofuel Tools to Household Products
June 2, 2014 – 11:05 am | No Comment

by Stephanie Storm (The New York Times)  Consumer products containing ingredients made using an advanced form of engineering known as synthetic biology are beginning to show up more often on grocery and department store shelves.
A …

Why the Promise of Cheap Fuel from Super Bugs Fell Short
February 6, 2014 – 5:35 pm | No Comment

by Martin LaMonica (MIT Technology Review)  The sell-off of synthetic biology pioneer LS9 goes to show that making biofuels from genetically engineered microbes has yet to deliver economically.

LS9 had hoped to be selling diesel to …

Help, I’ve Fallen and My Enterprise Can’t Get Up: Goldilocks, Right-Sizing and Synth-Bio
December 16, 2013 – 1:23 pm | No Comment

by Jim Lane (Biofuels Digest)  The story of Pareto Biotechnologies, RuBisCo, the pesky failures of evolution, and help for those who have fallen and can’t get up, via a right-sized approach.   Not too high a …

Embracing Open-source Biotech: DNA Freeware May Out-Innovate Patented Genes
September 3, 2013 – 3:36 pm | No Comment

(Lux Research)  Corporations will need to integrate open source with traditional patents for biotech innovations in medicine, renewable materials, and nutrition, Lux Research says
With synthetic biology (synbio) rapidly gaining momentum, and a landmark U.S. Supreme …

NSF Accepting Grant Applications under BBBE Program
August 26, 2013 – 7:00 pm | No Comment

by Erin Voegele (Ethanol Producer Magazine)  The National Science Foundation recently opened a new funding opportunity under its Biotechnology, Biochemical, and Biomass Engineering program. According to the grant notice, the program supports fundamental engineering research …

Exxon at Least 25 Years Away From Making Fuel From Algae
March 8, 2013 – 10:50 am | No Comment

by Joe Carroll (Bloomberg) Exxon Mobil Corp. (XOM)’s $600 million foray into creating motor fuels from algae may not succeed for at least another 25 years because of technical hurdles, said Chairman and Chief Executive …

The Dew Drop Inn — Who’s Dropping in What in Biofuels?
February 19, 2013 – 4:20 pm | No Comment

by Jim Lane (Biofuels Digest)  B20, B5, B100, E10, E22, E15, M50, E85, Bu12.5, HEFA 50.  Is your head swimming with acronyms and blend ratios?  Who exactly is making drop-in fuels, and what does that …

How Joule May Turn Biofuels Upside Down
July 20, 2012 – 4:24 pm | No Comment

by Jim Lane (Biofuels Digest)  …But some of the most interesting work being done today at Joule Unlimited is of the “Don’t Bee” type: progressively knocking out characteristics and pathways that create limitations on biofuels …

CAD for RNA: Joint BioEnergy Institute Researchers Develop CAD-Type Tools for Engineering RNA Control Systems
December 30, 2011 – 2:15 pm | No Comment

by Lynn Yarris (Lawrence Berkeley National Laboratory)  The computer assisted design (CAD) tools that made it possible to fabricate integrated circuits with millions of transistors may soon be coming to the biological sciences. Researchers at …

Friends of the Earth Calls for Moratorium on Synthetic Bio-Based Biofuels
October 4, 2010 – 8:49 am | No Comment

by Jim Lane (Biofuels Digest)  In Washington, Friends of the Earth released a report “Synthetic Solutions to the Climate Crisis: The Dangers of Synthetic Biology for Biofuels Production,” concluding that synthetic biology projects including the …

Synthetic Bio Could Cure Energy Woes
December 4, 2009 – 3:17 pm | No Comment

by Ph.D. Angelo DePalma (CheckBiotech, Genetic Engineering & Biotechnology News)   …“It is about systems,” says A. Malcolm Campbell, Ph.D., professor of biology at Davidson College, “not manipulating one or two genes, but whole pathways.” For …

Race To The Pump
November 30, -0001 – 12:00 am | No Comment

by Stephen K. Ritter (Chemical & Engineering News)  Chemists, chemical engineers, and synthetic biologists have largely met the technical challenge of developing biofuels to supplement and then replace petroleum-derived transportation fuels in the coming decades. …